Canine VEGF antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-VEGF-Ag01	Recombinant Canine VEGF protein	3090
GMP-CAN-VEGF-Ab01	Anti-Canine VEGF mouse monoclonal antibody (mAb)	1953
GMP-CAN-VEGF-Ab02	Anti-Canine VEGF mouse monoclonal antibody (mAb)	1953
GMP-CAN-VEGF-Ab03	Anti-Canine VEGF human monoclonal antibody (mAb)	1953
GMP-CAN-VEGF-Ab04	Anti-Canine VEGF human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-VEGF-Ag01
Product Name	Recombinant Canine VEGF protein
Target/Biomarker	Canine Vascular Endothelial Growth Factor (SPA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Vascular Endothelial Growth Factor antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SPA level test of animal Dog/Canine with angiogenesis.
Tag	His
Products description	Recombinant Canine VEGF protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-VEGF-Ab01, GMP-CAN-VEGF-Ab02
Product Name	Anti-Canine VEGF mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Vascular Endothelial Growth Factor (SPA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Vascular Endothelial Growth Factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies in SPA level test of animal Dog/Canine with angiogenesis.
Tag	mFc
Products description	Anti-Canine VEGF mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-VEGF-Ab03, GMP-CAN-VEGF-Ab04
Product Name	Anti-Canine VEGF human monoclonal antibody (mAb)
Target/Biomarker	Canine Vascular Endothelial Growth Factor (SPA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Vascular Endothelial Growth Factor antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies in SPA level test of animal Dog/Canine with angiogenesis.
Tag	hFc
Products description	Anti-Canine VEGF human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine Vascular Endothelial Growth Factor (cVEGF) stands at the nexus of canine physiology, driving the intricate process of angiogenesis, or blood vessel formation. This remarkable biomarker is encoded by the VEGF-A gene, producing several isoforms with distinct receptor affinities, allowing for precise control of vascular development in dogs. At its core, cVEGF is a glycoprotein, mainly expressed in endothelial cells—the very cells that line the interior of blood vessels. Its primary mission is to usher in the formation of new blood vessels, ensuring that oxygen and nutrients reach the tissues that need them. This process is not limited to any specific stage of life; rather, it is a continuous, dynamic mechanism required for various physiological phenomena in dogs. During embryonic development, cVEGF guides the creation of the intricate vascular network that will sustain the growing fetus. In adult dogs, it remains a guardian of health, facilitating wound healing by stimulating the growth of new blood vessels at the site of injury. Additionally, cVEGF plays a pivotal role in reproductive processes, ensuring proper vascularization of the uterus during pregnancy.

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