Canine TNFα antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-TNFa-Ag01	Recombinant Canine TNFα protein	3090
GMP-CAN-TNFa-Ab01	Anti-Canine TNFα mouse monoclonal antibody (mAb)	1953
GMP-CAN-TNFa-Ab02	Anti-Canine TNFα mouse monoclonal antibody (mAb)	1953
GMP-CAN-TNFa-Ab03	Anti-Canine TNFα human monoclonal antibody (mAb)	1953
GMP-CAN-TNFa-Ab04	Anti-Canine TNFα human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-TNFa-Ag01
Product Name	Recombinant Canine TNFα protein
Target/Biomarker	Canine tumor necrosis factor alpha (S100B)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine tumor necrosis factor alpha antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100B level test of animal Dog/Canine with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	His
Products description	Recombinant Canine TNFα protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-TNFa-Ab01, GMP-CAN-TNFa-Ab02
Product Name	Anti-Canine TNFα mouse monoclonal antibody (mAb)
Target/Biomarker	Canine tumor necrosis factor alpha (S100B)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine tumor necrosis factor alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies in S100B level test of animal Dog/Canine with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	mFc
Products description	Anti-Canine TNFα mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-TNFa-Ab03, GMP-CAN-TNFa-Ab04
Product Name	Anti-Canine TNFα human monoclonal antibody (mAb)
Target/Biomarker	Canine tumor necrosis factor alpha (S100B)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine tumor necrosis factor alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies in S100B level test of animal Dog/Canine with rheumatoid arthritis, ankylosing spondylitis, and Crohn’s disease.
Tag	hFc
Products description	Anti-Canine TNFα human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

TNFα, or Tumor Necrosis Factor Alpha, in dogs (canines), is a multifaceted cytokine with pivotal roles in both immune responses and inflammatory processes. As a member of the tumor necrosis factor superfamily, TNFα is a critical mediator of various physiological functions, including inflammation, apoptosis, cell proliferation, and immune cell activation. Structurally, TNFα exists as a homotrimeric protein, composed of three identical subunits. These subunits interact with specific cell surface receptors, TNFR1 (TNF receptor 1) and TNFR2 (TNF receptor 2), initiating intricate signaling cascades. TNFα's pleiotropic nature means it can have diverse effects depending on the context and the receptors engaged.

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