Canine TK1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-TK1-Ag01	Recombinant Canine TK1 protein	3090
GMP-CAN-TK1-Ab01	Anti-Canine TK1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-TK1-Ab02	Anti-Canine TK1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-TK1-Ab03	Anti-Canine TK1 human monoclonal antibody (mAb)	1953
GMP-CAN-TK1-Ab04	Anti-Canine TK1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-TK1-Ag01
Product Name	Recombinant Canine TK1 protein
Target/Biomarker	Canine Thymidine Kinase 1 (S100-A9)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Thymidine Kinase 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Dog/Canine with hematological malignancies.
Tag	His
Products description	Recombinant Canine TK1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-TK1-Ab01, GMP-CAN-TK1-Ab02
Product Name	Anti-Canine TK1 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Thymidine Kinase 1 (S100-A9)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Thymidine Kinase 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Dog/Canine with hematological malignancies.
Tag	mFc
Products description	Anti-Canine TK1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-TK1-Ab03, GMP-CAN-TK1-Ab04
Product Name	Anti-Canine TK1 human monoclonal antibody (mAb)
Target/Biomarker	Canine Thymidine Kinase 1 (S100-A9)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Thymidine Kinase 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Dog/Canine with hematological malignancies.
Tag	hFc
Products description	Anti-Canine TK1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Thymidine Kinase 1 (TK1) is an enzyme that holds critical importance in canine health, particularly in the sphere of DNA synthesis and cell proliferation. This biomarker is an essential player in the intricate process of DNA replication, facilitating the phosphorylation of thymidine, a nucleoside crucial for constructing DNA molecules. TK1's enzymatic activity ensures the availability of nucleotides required for DNA replication, a fundamental process in cell division and growth. In dogs, TK1 is released into the bloodstream, where its levels can be quantified through blood tests. Elevated levels of TK1 often indicate increased cellular proliferation, which can occur in various medical conditions. While TK1 is not specific to any particular disease, its elevation can signal the presence of underlying health issues, such as cancer or certain viral infections. TK1 serves as a dynamic and responsive biomarker, reflecting changes in cellular activity. In cancer, for instance, the uncontrolled growth and division of cells lead to higher TK1 levels in the bloodstream. Consequently, monitoring TK1 can offer valuable insights into the proliferative status of cells, aiding in disease diagnosis, staging, and treatment assessment.

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