Canine Serum amyloid A antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Serum-amyloid-A-Ag01	Recombinant Canine Serum amyloid A protein	3090
GMP-CAN-Serum-amyloid-A-Ab01	Anti-Canine Serum amyloid A mouse monoclonal antibody (mAb)	3090
GMP-CAN-Serum-amyloid-A-Ab02	Anti-Canine Serum amyloid A mouse monoclonal antibody (mAb)	3090
GMP-CAN-Serum-amyloid-A-Ab03	Anti-Canine Serum amyloid A human monoclonal antibody (mAb)	3090
GMP-CAN-Serum-amyloid-A-Ab04	Anti-Canine Serum amyloid A human monoclonal antibody (mAb)	3090

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-Serum-amyloid-A-Ag01
Product Name	Recombinant Canine Serum amyloid A protein
Target/Biomarker	Canine Serum Amyloid A (SAA)
Alias of Target/Biomarker	Canine Serum Amyloid A (SAA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Serum Amyloid A antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAA level test of animal Dog/Canine with Acute inflammation, infections.
Tag	His
Products description	Recombinant Canine Serum amyloid A protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Serum-amyloid-A-Ab01, GMP-CAN-Serum-amyloid-A-Ab02
Product Name	Anti-Canine Serum amyloid A mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Serum Amyloid A (SAA)
Alias of Target/Biomarker	Canine Serum Amyloid A (SAA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Serum Amyloid A antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Dog/Canine with Acute inflammation, infections.
Tag	mFc
Products description	Anti-Canine Serum amyloid A mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Serum-amyloid-A-Ab03, GMP-CAN-Serum-amyloid-A-Ab04
Product Name	Anti-Canine Serum amyloid A human monoclonal antibody (mAb)
Target/Biomarker	Canine Serum Amyloid A (SAA)
Alias of Target/Biomarker	Canine Serum Amyloid A (SAA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Serum Amyloid A antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Dog/Canine with Acute inflammation, infections.
Tag	hFc
Products description	Anti-Canine Serum amyloid A human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

SAA, or Serum Amyloid A, is a remarkable biomarker that occupies a central position in the immune response of dogs (canines) to inflammatory challenges. This protein is primarily synthesized by hepatocytes in the liver and is swiftly released into the bloodstream in response to various inflammatory signals. Its role as an acute-phase protein is fundamental to the canine immune system's ability to detect and combat inflammation, infection, and tissue damage. Structurally, SAA comprises two primary isoforms in dogs, SAA1 and SAA2, both of which can be elevated during inflammatory conditions. These isoforms play a pivotal role in modulating the host's immune response to pathogens and injuries. SAA acts as a chemoattractant for immune cells, facilitating their migration to the site of infection or inflammation. Additionally, SAA can influence other immune responses, including the production of cytokines and other inflammatory mediators. In dogs, SAA serves as a sensitive and early marker of systemic inflammation. When exposed to inflammatory stimuli, such as infections, tissue damage, or other inflammatory conditions, the liver rapidly increases the synthesis of SAA. Elevated levels of SAA in the bloodstream can be detected within hours of the initial trigger, making it a valuable diagnostic tool for veterinarians.

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