Canine SAHH antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-SAHH-Ag01	Recombinant Canine SAHH protein	3090
GMP-CAN-SAHH-Ab01	Anti-Canine SAHH mouse monoclonal antibody (mAb)	1953
GMP-CAN-SAHH-Ab02	Anti-Canine SAHH mouse monoclonal antibody (mAb)	1953
GMP-CAN-SAHH-Ab03	Anti-Canine SAHH human monoclonal antibody (mAb)	1953
GMP-CAN-SAHH-Ab04	Anti-Canine SAHH human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-SAHH-Ag01
Product Name	Recombinant Canine SAHH protein
Target/Biomarker	Canine S-adenosylhomocysteine (SAHH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine S-adenosylhomocysteine antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of animal Dog/Canine with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
Tag	His
Products description	Recombinant Canine SAHH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-SAHH-Ab01, GMP-CAN-SAHH-Ab02
Product Name	Anti-Canine SAHH mouse monoclonal antibody (mAb)
Target/Biomarker	Canine S-adenosylhomocysteine (SAHH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine S-adenosylhomocysteine antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Dog/Canine with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
Tag	mFc
Products description	Anti-Canine SAHH mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-SAHH-Ab03, GMP-CAN-SAHH-Ab04
Product Name	Anti-Canine SAHH human monoclonal antibody (mAb)
Target/Biomarker	Canine S-adenosylhomocysteine (SAHH)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine S-adenosylhomocysteine antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Dog/Canine with S-adenosylhomocysteine (AdoHcy) hydrolase deficiency.
Tag	hFc
Products description	Anti-Canine SAHH human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine SAHH (S-Adenosylhomocysteine Hydrolase) is a cornerstone biomarker, deeply integrated into the intricacies of canine biology. It takes its place within the canine species, Canis lupus familiaris, as a key player in the realm of methylation, an essential cellular process that orchestrates a multitude of biochemical reactions. Methylation, at its core, involves the transfer of a methyl group from one molecule to another, a process vital for regulating gene expression, protein synthesis, and metabolic pathways within cells. As this dance of molecular modification unfolds, S-Adenosylhomocysteine (SAH) emerges as a byproduct. SAHH steps onto the stage as a pivotal enzyme, catalyzing the conversion of SAH into adenosine and homocysteine. This transformation is more than a mere biochemical reaction; it's a linchpin that ensures the proper flow of cellular processes by preventing the accumulation of SAH, which can inhibit the efficiency of methylation reactions. The importance of Canine SAHH extends beyond its role as a regulator of SAH levels. It embodies the guardian of methylation, the guardian of cellular harmony, safeguarding the intricate balance of molecular modifications within canine cells. By doing so, it plays a vital role in fine-tuning the cellular orchestra, influencing gene expression, enzymatic activities, and metabolic pathways that underpin canine health and well-being.

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