Canine Pregnancy-associated glycoprotein 1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Preg-ass-gly-1-Ag01	Recombinant Canine Pregnancy-associated glycoprotein 1 protein	3090
GMP-CAN-Preg-ass-gly-1-Ab01	Anti-Canine Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-Preg-ass-gly-1-Ab02	Anti-Canine Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	1953
GMP-CAN-Preg-ass-gly-1-Ab03	Anti-Canine Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	1953
GMP-CAN-Preg-ass-gly-1-Ab04	Anti-Canine Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-Preg-ass-gly-1-Ag01
Product Name	Recombinant Canine Pregnancy-associated glycoprotein 1 protein
Target/Biomarker	Canine Pregnancy-associated glycoprotein 1 ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Pregnancy-associated glycoprotein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with N/A.
Tag	His
Products description	Recombinant Canine Pregnancy-associated glycoprotein 1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Preg-ass-gly-1-Ab01, GMP-CAN-Preg-ass-gly-1-Ab02
Product Name	Anti-Canine Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Pregnancy-associated glycoprotein 1 ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Pregnancy-associated glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with N/A.
Tag	mFc
Products description	Anti-Canine Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Preg-ass-gly-1-Ab03, GMP-CAN-Preg-ass-gly-1-Ab04
Product Name	Anti-Canine Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)
Target/Biomarker	Canine Pregnancy-associated glycoprotein 1 ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Pregnancy-associated glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with N/A.
Tag	hFc
Products description	Anti-Canine Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

As of my last update in April 2023, the specific study or application of Pregnancy-associated glycoprotein 1 (PAG1) in dogs (canines) for pregnancy diagnosis or monitoring is not broadly documented in veterinary practice or literature. The concept of pregnancy-associated glycoproteins (PAGs) has been extensively explored in ruminants, like cattle and sheep, where PAGs are recognized as reliable markers of pregnancy and are used for early detection and monitoring purposes. PAGs are produced by the placenta and serve various functions, including supporting the maternal recognition of pregnancy and modulating the maternal immune system to favor pregnancy maintenance. In canine pregnancy diagnosis and monitoring, the focus tends to be on other methods and markers: Relaxin Hormone Assays: Relaxin, a hormone produced by the placenta, is a key biomarker for confirming pregnancy in dogs. Commercially available relaxin tests can detect pregnancy as early as 22-30 days post-breeding. Relaxin levels remain elevated throughout pregnancy, making it a reliable indicator. Ultrasound: Ultrasound is a primary diagnostic tool used to confirm pregnancy in dogs, typically starting around 25-30 days post-breeding. It allows for visualization of the gestational sacs, developing fetuses, and assessment of fetal health. Radiography (X-rays): X-rays are useful later in pregnancy (usually after 45 days post-breeding) for counting the number of fetuses and assessing skeletal development. This method helps in preparing for whelping but is not suitable for early pregnancy diagnosis. Physical Examination and Palpation: Veterinary practitioners may use physical examination and palpation techniques to suggest pregnancy, particularly in the mid to late stages. However, these methods are less definitive without the support of imaging or hormonal assays. Progesterone Levels: Monitoring progesterone levels is useful around the time of breeding to confirm ovulation and optimal mating times but not for diagnosing pregnancy itself. While PAGs play significant roles in the pregnancies of other mammals, especially in species like cattle, their study, identification, and application in canine pregnancy remain limited in scope. Research in veterinary medicine continues to evolve, and future discoveries may expand the toolkit for pregnancy diagnosis and monitoring in dogs, potentially including markers like PAG1 if their relevance to canine pregnancy is established and validated. For the most accurate and up-to-date information on canine pregnancy diagnosis and the potential role of PAGs or other emerging biomarkers, consultation with veterinary reproductive specialists and review of current veterinary literature are recommended.

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