Canine Pregnancy Specific Protein B antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Pre-Spec-Pro-B-Ag01	Recombinant Canine Pregnancy Specific Protein B protein	3090
GMP-CAN-Pre-Spec-Pro-B-Ab01	Anti-Canine Pregnancy Specific Protein B mouse monoclonal antibody (mAb)	1953
GMP-CAN-Pre-Spec-Pro-B-Ab02	Anti-Canine Pregnancy Specific Protein B mouse monoclonal antibody (mAb)	1953
GMP-CAN-Pre-Spec-Pro-B-Ab03	Anti-Canine Pregnancy Specific Protein B human monoclonal antibody (mAb)	1953
GMP-CAN-Pre-Spec-Pro-B-Ab04	Anti-Canine Pregnancy Specific Protein B human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-Pre-Spec-Pro-B-Ag01
Product Name	Recombinant Canine Pregnancy Specific Protein B protein
Target/Biomarker	Canine Pregnancy Specific Protein B ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Pregnancy Specific Protein B antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with N/A.
Tag	His
Products description	Recombinant Canine Pregnancy Specific Protein B protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Pre-Spec-Pro-B-Ab01, GMP-CAN-Pre-Spec-Pro-B-Ab02
Product Name	Anti-Canine Pregnancy Specific Protein B mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Pregnancy Specific Protein B ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Pregnancy Specific Protein B antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with N/A.
Tag	mFc
Products description	Anti-Canine Pregnancy Specific Protein B mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Pre-Spec-Pro-B-Ab03, GMP-CAN-Pre-Spec-Pro-B-Ab04
Product Name	Anti-Canine Pregnancy Specific Protein B human monoclonal antibody (mAb)
Target/Biomarker	Canine Pregnancy Specific Protein B ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Pregnancy Specific Protein B antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with N/A.
Tag	hFc
Products description	Anti-Canine Pregnancy Specific Protein B human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Pregnancy-Specific Protein B (PSPB) is primarily associated with bovine pregnancy as a biomarker for early detection. In dogs (canines), PSPB is not a recognized marker for pregnancy detection. Instead, canine pregnancy diagnosis relies on different methods and markers, including: Relaxin: Relaxin is a hormone produced by the placental tissues in pregnant dogs and serves as a key biochemical marker for confirming pregnancy. Commercial tests are available to detect relaxin in the blood serum of pregnant dogs, typically from about 22 to 30 days post-breeding. Relaxin's presence at elevated levels is a reliable indicator of pregnancy because its production is closely associated with the development of the placenta. Ultrasound: Ultrasound examination is a common and reliable method for diagnosing pregnancy in dogs, usually starting around 25 to 30 days post-breeding. It allows for the visualization of the gestational sacs and, later in the pregnancy, fetal structures and heartbeats. Radiography (X-rays): X-rays are another diagnostic tool, generally used later in pregnancy (around 45 to 55 days post-breeding) to determine the number of fetuses and assess fetal development and skeletal structure. This method is not suitable for early pregnancy detection but is valuable for planning for whelping. Physical Examination and Hormonal Changes: Veterinarians may also use physical examination findings and changes in hormonal levels (other than relaxin) to infer pregnancy. However, these methods are less specific and can be influenced by other factors. Progesterone Levels: While not a direct marker of pregnancy, monitoring progesterone levels can help confirm ovulation and optimal breeding times, indirectly aiding in the prediction of a successful pregnancy. In summary, while PSPB is a specific marker used in cattle, canine pregnancy diagnosis does not rely on PSPB but rather on a combination of hormonal assays (like relaxin), imaging techniques (ultrasound and radiography), and physical examination findings. These methods collectively offer a comprehensive approach to confirming pregnancy in dogs.

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