Canine PSA antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-PSA-Ag01	Recombinant Canine PSA protein	3090
GMP-CAN-PSA-Ab01	Anti-Canine PSA mouse monoclonal antibody (mAb)	1953
GMP-CAN-PSA-Ab02	Anti-Canine PSA mouse monoclonal antibody (mAb)	1953
GMP-CAN-PSA-Ab03	Anti-Canine PSA human monoclonal antibody (mAb)	1953
GMP-CAN-PSA-Ab04	Anti-Canine PSA human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-PSA-Ag01
Product Name	Recombinant Canine PSA protein
Target/Biomarker	Canine Prostate-specific antigen (PSA)
Alias of Target/Biomarker	Canine Prostate-Specific Antigen (PSA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Prostate-specific antigen antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PSA level test of animal Dog/Canine with prostate cancer.
Tag	His
Products description	Recombinant Canine PSA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PSA-Ab01, GMP-CAN-PSA-Ab02
Product Name	Anti-Canine PSA mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Prostate-specific antigen (PSA)
Alias of Target/Biomarker	Canine Prostate-Specific Antigen (PSA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Prostate-specific antigen antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PSA antibodies in PSA level test of animal Dog/Canine with prostate cancer.
Tag	mFc
Products description	Anti-Canine PSA mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PSA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PSA-Ab03, GMP-CAN-PSA-Ab04
Product Name	Anti-Canine PSA human monoclonal antibody (mAb)
Target/Biomarker	Canine Prostate-specific antigen (PSA)
Alias of Target/Biomarker	Canine Prostate-Specific Antigen (PSA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Prostate-specific antigen antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PSA antibodies in PSA level test of animal Dog/Canine with prostate cancer.
Tag	hFc
Products description	Anti-Canine PSA human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PSA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Prostate-Specific Antigen (PSA) in dogs (canines) is a glycoprotein enzyme with a specific role in male reproductive physiology. PSA is primarily produced by the prostate gland and is essential for the liquefaction of semen following ejaculation. This enzymatic action aids in sperm mobility and fertilization. Structurally, PSA is classified as a serine protease, and its expression is regulated by androgens, the male sex hormones. In healthy male dogs, PSA is predominantly found within the prostate tissue, where it is synthesized by the prostate epithelial cells. It is subsequently secreted into the seminal fluid, where it exerts its enzymatic activity. PSA is recognized for its specificity to the prostate, making it a valuable biomarker for assessing prostate health. PSA levels can be measured in the bloodstream, but it's important to note that in healthy dogs, these levels are typically low. Various factors can influence PSA levels, including age and breed. Age-related changes in the prostate can lead to modest increases in PSA levels, which are considered normal in older dogs.

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