Canine PIIINP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-PIIINP-Ag01	Recombinant Canine PIIINP protein	3090
GMP-CAN-PIIINP-Ab01	Anti-Canine PIIINP mouse monoclonal antibody (mAb)	1953
GMP-CAN-PIIINP-Ab02	Anti-Canine PIIINP mouse monoclonal antibody (mAb)	1953
GMP-CAN-PIIINP-Ab03	Anti-Canine PIIINP human monoclonal antibody (mAb)	1953
GMP-CAN-PIIINP-Ab04	Anti-Canine PIIINP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-PIIINP-Ag01
Product Name	Recombinant Canine PIIINP protein
Target/Biomarker	Canine Procollagen III N-terminal peptide (PIIINP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Procollagen III N-terminal peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
Tag	His
Products description	Recombinant Canine PIIINP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PIIINP-Ab01, GMP-CAN-PIIINP-Ab02
Product Name	Anti-Canine PIIINP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Procollagen III N-terminal peptide (PIIINP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Procollagen III N-terminal peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PIIINP antibodies in PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
Tag	mFc
Products description	Anti-Canine PIIINP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PIIINP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PIIINP-Ab03, GMP-CAN-PIIINP-Ab04
Product Name	Anti-Canine PIIINP human monoclonal antibody (mAb)
Target/Biomarker	Canine Procollagen III N-terminal peptide (PIIINP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Procollagen III N-terminal peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PIIINP antibodies in PIIINP level test of animal Dog/Canine with liver fibrosis and cirrhosis.
Tag	hFc
Products description	Anti-Canine PIIINP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PIIINP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Canine Procollagen Type III N-Terminal Propeptide (PIIINP) emerges as a linchpin in the intricate world of connective tissues within dogs. Functionally, PIIINP serves as a sentinel, a molecular messenger that reveals the ongoing story of collagen synthesis and connective tissue remodeling. Structurally, PIIINP is derived from the precursor molecule procollagen Type III. During collagen production, procollagen undergoes enzymatic processing, resulting in the formation of collagen fibers. PIIINP represents the N-terminal propeptide of this collagen subtype, a marker for the inception of collagen synthesis. Collagen, the primary structural protein in connective tissues, underpins the strength, flexibility, and resilience of tissues such as skin, tendons, and blood vessels. The continuous synthesis and degradation of collagen are pivotal processes, ensuring the dynamic adaptation and repair of these tissues. PIIINP, by virtue of its presence in collagen synthesis, offers a glimpse into this remarkable process. When connective tissues undergo remodeling or repair, PIIINP levels often fluctuate in response to changing demands. For instance, during wound healing, PIIINP production surges as the body mobilizes collagen to mend damaged tissue. Conversely, in pathological conditions like fibrosis, characterized by excessive collagen deposition, PIIINP levels can be persistently elevated, reflecting the ongoing fibrotic process.

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