Canine PCT antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-PCT-Ag01	Recombinant Canine PCT protein	3090
GMP-CAN-PCT-Ab01	Anti-Canine PCT mouse monoclonal antibody (mAb)	1953
GMP-CAN-PCT-Ab02	Anti-Canine PCT mouse monoclonal antibody (mAb)	1953
GMP-CAN-PCT-Ab03	Anti-Canine PCT human monoclonal antibody (mAb)	1953
GMP-CAN-PCT-Ab04	Anti-Canine PCT human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-PCT-Ag01
Product Name	Recombinant Canine PCT protein
Target/Biomarker	Canine procalcitonin (PCT)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine procalcitonin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PCT level test of animal Dog/Canine with Bacterial infections, sepsis.
Tag	His
Products description	Recombinant Canine PCT protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PCT-Ab01, GMP-CAN-PCT-Ab02
Product Name	Anti-Canine PCT mouse monoclonal antibody (mAb)
Target/Biomarker	Canine procalcitonin (PCT)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine procalcitonin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PCT antibodies in PCT level test of animal Dog/Canine with Bacterial infections, sepsis.
Tag	mFc
Products description	Anti-Canine PCT mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PCT antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-PCT-Ab03, GMP-CAN-PCT-Ab04
Product Name	Anti-Canine PCT human monoclonal antibody (mAb)
Target/Biomarker	Canine procalcitonin (PCT)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine procalcitonin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PCT antibodies in PCT level test of animal Dog/Canine with Bacterial infections, sepsis.
Tag	hFc
Products description	Anti-Canine PCT human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PCT antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Procalcitonin (PCT) is a biomarker of growing significance in canine medicine, primarily linked to the presence of bacterial infections. While PCT's role as a precursor to calcitonin, a hormone regulating calcium levels in the body, is relatively minor in dogs, its utility as a marker for bacterial infections is substantial. In dogs exposed to bacterial pathogens, the immune system responds by producing PCT. Importantly, PCT levels rise significantly in response to severe and systemic bacterial infections, making it a valuable tool for diagnosis and management. This elevation occurs because PCT production is tightly regulated, and its release is minimal under normal conditions. However, when the body encounters bacterial invaders, especially those that lead to systemic infections, PCT production escalates rapidly. Measurement of PCT in dogs is typically accomplished through blood tests. By quantifying PCT levels, veterinarians gain a specific and sensitive means to identify bacterial infections, distinguish them from other causes of inflammation, and tailor treatment strategies accordingly.

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