Canine NT proBNP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-NT-proBNP-Ag01	Recombinant Canine NT proBNP protein	3090
GMP-CAN-NT-proBNP-Ab01	Anti-Canine NT proBNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-NT-proBNP-Ab02	Anti-Canine NT proBNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-NT-proBNP-Ab03	Anti-Canine NT proBNP human monoclonal antibody (mAb)	1953
GMP-CAN-NT-proBNP-Ab04	Anti-Canine NT proBNP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-NT-proBNP-Ag01
Product Name	Recombinant Canine NT proBNP protein
Target/Biomarker	Canine N-terminal prohormone of brain natriuretic peptide (NT proBNP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine N-terminal prohormone of brain natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NT proBNP level test of animal Dog/Canine with Heart failure, cardiac disease.
Tag	His
Products description	Recombinant Canine NT proBNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-NT-proBNP-Ab01, GMP-CAN-NT-proBNP-Ab02
Product Name	Anti-Canine NT proBNP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine N-terminal prohormone of brain natriuretic peptide (NT proBNP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine N-terminal prohormone of brain natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies in NT proBNP level test of animal Dog/Canine with Heart failure, cardiac disease.
Tag	mFc
Products description	Anti-Canine NT proBNP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-NT-proBNP-Ab03, GMP-CAN-NT-proBNP-Ab04
Product Name	Anti-Canine NT proBNP human monoclonal antibody (mAb)
Target/Biomarker	Canine N-terminal prohormone of brain natriuretic peptide (NT proBNP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine N-terminal prohormone of brain natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies in NT proBNP level test of animal Dog/Canine with Heart failure, cardiac disease.
Tag	hFc
Products description	Anti-Canine NT proBNP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

N-terminal pro-B-type natriuretic peptide (NT-proBNP) in dogs is a fragment of the B-type natriuretic peptide (BNP) precursor molecule, primarily synthesized and released from cardiac myocytes in response to myocardial stretch and stress. This biomarker has emerged as a cornerstone in veterinary cardiology, providing critical insights into canine cardiac health. The production of NT-proBNP is intimately linked to cardiac function in dogs. Specifically, the ventricles of the heart, notably the left ventricle, serve as the primary source of NT-proBNP secretion. When these cardiac muscles encounter stress, strain, or injury, such as in cases of valvular heart disease, dilated cardiomyopathy, or congestive heart failure (CHF), NT-proBNP is released into the bloodstream. NT-proBNP serves as a sensitive and specific indicator of cardiac stress and dysfunction in dogs. Its measurement allows veterinarians to assess the presence and severity of various cardiac diseases, facilitating early diagnosis and tailored treatment strategies.

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