Canine NGAL antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-NGAL-Ag01	Recombinant Canine NGAL protein	3090
GMP-CAN-NGAL-Ab01	Anti-Canine NGAL mouse monoclonal antibody (mAb)	1953
GMP-CAN-NGAL-Ab02	Anti-Canine NGAL mouse monoclonal antibody (mAb)	1953
GMP-CAN-NGAL-Ab03	Anti-Canine NGAL human monoclonal antibody (mAb)	1953
GMP-CAN-NGAL-Ab04	Anti-Canine NGAL human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-NGAL-Ag01
Product Name	Recombinant Canine NGAL protein
Target/Biomarker	Canine Neutrophil gelatinase-associated lipocalin (NGAL)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Neutrophil gelatinase-associated lipocalin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NGAL level test of animal Dog/Canine with kidney injury.
Tag	His
Products description	Recombinant Canine NGAL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-NGAL-Ab01, GMP-CAN-NGAL-Ab02
Product Name	Anti-Canine NGAL mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Neutrophil gelatinase-associated lipocalin (NGAL)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Neutrophil gelatinase-associated lipocalin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NGAL antibodies in NGAL level test of animal Dog/Canine with kidney injury.
Tag	mFc
Products description	Anti-Canine NGAL mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NGAL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-NGAL-Ab03, GMP-CAN-NGAL-Ab04
Product Name	Anti-Canine NGAL human monoclonal antibody (mAb)
Target/Biomarker	Canine Neutrophil gelatinase-associated lipocalin (NGAL)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Neutrophil gelatinase-associated lipocalin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NGAL antibodies in NGAL level test of animal Dog/Canine with kidney injury.
Tag	hFc
Products description	Anti-Canine NGAL human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NGAL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine NGAL, or Neutrophil Gelatinase-Associated Lipocalin, is a relatively small but mighty glycoprotein with far-reaching significance in the realm of canine health. It operates as a sentinel, a vigilant guardian of the intricate renal machinery within a dog's body, specifically, the renal tubules. Synthesized and released by various cells, including neutrophils and renal tubular cells, Canine NGAL is poised to respond to renal distress with remarkable speed. When acute kidney injury (AKI) strikes, whether due to toxins, infections, or other factors, Canine NGAL swiftly enters the bloodstream. This rapid release positions NGAL as one of the earliest indicators of renal dysfunction in dogs, often preceding other traditional markers. Canine NGAL's journey through the renal tubules holds critical insights into its role as a biomarker. In healthy dogs, the majority of NGAL is reabsorbed by the renal tubules and catabolized. However, in the presence of renal injury or stress, this finely tuned process is disrupted. As a result, NGAL levels rise, serving as a beacon of distress and an early warning system for veterinarians. The true strength of Canine NGAL is its sensitivity and specificity. It detects renal injury at its inception, often before clinical symptoms manifest. This early detection is a game-changer in the management of AKI, allowing for prompt intervention and treatment. Timely action can significantly improve the prognosis for canine patients, preserving both their quality of life and longevity.

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