Canine Myo antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-Myo-Ag01	Recombinant Canine Myo protein	3090
GMP-CAN-Myo-Ab01	Anti-Canine Myo mouse monoclonal antibody (mAb)	1953
GMP-CAN-Myo-Ab02	Anti-Canine Myo mouse monoclonal antibody (mAb)	1953
GMP-CAN-Myo-Ab03	Anti-Canine Myo human monoclonal antibody (mAb)	1953
GMP-CAN-Myo-Ab04	Anti-Canine Myo human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-Myo-Ag01
Product Name	Recombinant Canine Myo protein
Target/Biomarker	Canine Myoglobin (Myo)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Myoglobin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Myo level test of animal Dog/Canine with acute ischemic myocardial injury.
Tag	His
Products description	Recombinant Canine Myo protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Myo-Ab01, GMP-CAN-Myo-Ab02
Product Name	Anti-Canine Myo mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Myoglobin (Myo)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Myoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Myo antibodies in Myo level test of animal Dog/Canine with acute ischemic myocardial injury.
Tag	mFc
Products description	Anti-Canine Myo mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Myo antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-Myo-Ab03, GMP-CAN-Myo-Ab04
Product Name	Anti-Canine Myo human monoclonal antibody (mAb)
Target/Biomarker	Canine Myoglobin (Myo)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Myoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Myo antibodies in Myo level test of animal Dog/Canine with acute ischemic myocardial injury.
Tag	hFc
Products description	Anti-Canine Myo human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Myo antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Myoglobin (Myo) in dogs is a globular protein with a vital role in muscle function and oxygen transport. Structurally similar to hemoglobin, Myoglobin contains a heme group that binds and releases oxygen as needed within muscle tissues. This property is particularly significant in canines, where Myoglobin ensures an uninterrupted oxygen supply to muscles during periods of increased activity, exercise, or muscle contraction. The presence of Myoglobin in canine muscle cells is integral to sustaining optimal muscle function. When muscles contract, they require a steady supply of oxygen to generate energy and power the contraction process. Myoglobin serves as an oxygen reservoir, binding with oxygen when its concentration is high within muscle tissue and releasing it when oxygen availability diminishes during muscle contraction. This dynamic mechanism helps maintain muscle oxygenation and supports canine mobility and performance. Importantly, Myoglobin in dogs has a distinct attribute that makes it invaluable in veterinary medicine. When muscle cells experience injury, damage, or inflammation, Myoglobin is released into the bloodstream. This phenomenon forms the basis for utilizing Myoglobin as a biomarker for assessing muscle health. The measurement of Myoglobin levels in blood tests provides veterinarians with a direct indicator of potential muscle issues, allowing for early diagnosis and intervention.

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