Canine MMP3 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-MMP3-Ag01	Recombinant Canine MMP3 protein	3090
GMP-CAN-MMP3-Ab01	Anti-Canine MMP3 mouse monoclonal antibody (mAb)	1953
GMP-CAN-MMP3-Ab02	Anti-Canine MMP3 mouse monoclonal antibody (mAb)	1953
GMP-CAN-MMP3-Ab03	Anti-Canine MMP3 human monoclonal antibody (mAb)	1953
GMP-CAN-MMP3-Ab04	Anti-Canine MMP3 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-MMP3-Ag01
Product Name	Recombinant Canine MMP3 protein
Target/Biomarker	Canine matrix metalloproteinase-3 (MMP3)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine matrix metalloproteinase-3 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in MMP3 level test of animal Dog/Canine with cancer, asthma and rheumatoid arthritis.
Tag	His
Products description	Recombinant Canine MMP3 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-MMP3-Ab01, GMP-CAN-MMP3-Ab02
Product Name	Anti-Canine MMP3 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine matrix metalloproteinase-3 (MMP3)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine matrix metalloproteinase-3 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MMP3 antibodies in MMP3 level test of animal Dog/Canine with cancer, asthma and rheumatoid arthritis.
Tag	mFc
Products description	Anti-Canine MMP3 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MMP3 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-MMP3-Ab03, GMP-CAN-MMP3-Ab04
Product Name	Anti-Canine MMP3 human monoclonal antibody (mAb)
Target/Biomarker	Canine matrix metalloproteinase-3 (MMP3)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine matrix metalloproteinase-3 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MMP3 antibodies in MMP3 level test of animal Dog/Canine with cancer, asthma and rheumatoid arthritis.
Tag	hFc
Products description	Anti-Canine MMP3 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-MMP3 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Matrix Metalloproteinase-3 (MMP-3), also known as stromelysin-1, stands as a multifaceted enzymatic entity within the canine biological landscape. It is part of the matrix metalloproteinase family, a group of enzymes renowned for their profound impact on tissue remodeling, repair, and maintenance in dogs. Structurally, MMP-3 is a zinc-dependent endopeptidase, featuring a catalytic domain that enables it to cleave specific components of the extracellular matrix (ECM). Its substrate range encompasses key ECM constituents, including collagen, proteoglycans, and fibronectin. This proteolytic capability allows MMP-3 to play a central role in orchestrating tissue remodeling processes in dogs. MMP-3's enzymatic activity is tightly regulated under normal physiological conditions. However, it can become dysregulated in various pathological states, leading to excessive ECM degradation and tissue damage. This dysregulation can manifest in several canine health conditions.

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