Canine HE4 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-HE4-Ag01	Recombinant Canine HE4 protein	3090
GMP-CAN-HE4-Ab01	Anti-Canine HE4 mouse monoclonal antibody (mAb)	1953
GMP-CAN-HE4-Ab02	Anti-Canine HE4 mouse monoclonal antibody (mAb)	1953
GMP-CAN-HE4-Ab03	Anti-Canine HE4 human monoclonal antibody (mAb)	1953
GMP-CAN-HE4-Ab04	Anti-Canine HE4 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-HE4-Ag01
Product Name	Recombinant Canine HE4 protein
Target/Biomarker	Canine epididymis protein 4 (HE4)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine epididymis protein 4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HE4 level test of animal Dog/Canine with ovarian cancer.
Tag	His
Products description	Recombinant Canine HE4 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-HE4-Ab01, GMP-CAN-HE4-Ab02
Product Name	Anti-Canine HE4 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Dog/Canine with ovarian cancer.
Tag	mFc
Products description	Anti-Canine HE4 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-HE4-Ab03, GMP-CAN-HE4-Ab04
Product Name	Anti-Canine HE4 human monoclonal antibody (mAb)
Target/Biomarker	Canine epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Dog/Canine with ovarian cancer.
Tag	hFc
Products description	Anti-Canine HE4 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Dog/Canine HE4, known as Human Epididymis Protein 4 (HE4), is a noteworthy protein antigen primarily detected in the blood serum of domestic dogs (Canis lupus familiaris). It belongs to the glycoprotein family and holds a multifaceted role in canine health assessments. HE4's molecular structure comprises carbohydrate chains bound to a protein core, making it distinguishable within the complex milieu of blood serum constituents. This distinct structure enables accurate measurement and monitoring, offering insights into the health status of the canine patient.HE4's significance in canine health is particularly notable in the context of reproductive and gynecological health, primarily in female dogs. While its specific functions in dogs are still under investigation, it is believed to play a role in various physiological processes, including ovarian function. Consequently, elevated HE4 levels can indicate underlying health issues or diseases, making it a valuable diagnostic biomarker in veterinary medicine.

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