Canine HABP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-HABP-Ag01	Recombinant Canine HABP protein	3090
GMP-CAN-HABP-Ab01	Anti-Canine HABP mouse monoclonal antibody (mAb)	1953
GMP-CAN-HABP-Ab02	Anti-Canine HABP mouse monoclonal antibody (mAb)	1953
GMP-CAN-HABP-Ab03	Anti-Canine HABP human monoclonal antibody (mAb)	1953
GMP-CAN-HABP-Ab04	Anti-Canine HABP human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-CAN-HABP-Ag01
Product Name	Recombinant Canine HABP protein
Target/Biomarker	Canine Hyaluronic acid binding protein (HABP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Hyaluronic acid binding protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HABP level test of animal Dog/Canine with rheumatoid arthritis (RA) andosteoarthritis.
Tag	His
Products description	Recombinant Canine HABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-HABP-Ab01, GMP-CAN-HABP-Ab02
Product Name	Anti-Canine HABP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Hyaluronic acid binding protein (HABP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Hyaluronic acid binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HABP antibodies in HABP level test of animal Dog/Canine with rheumatoid arthritis (RA) andosteoarthritis.
Tag	mFc
Products description	Anti-Canine HABP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-HABP-Ab03, GMP-CAN-HABP-Ab04
Product Name	Anti-Canine HABP human monoclonal antibody (mAb)
Target/Biomarker	Canine Hyaluronic acid binding protein (HABP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Hyaluronic acid binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HABP antibodies in HABP level test of animal Dog/Canine with rheumatoid arthritis (RA) andosteoarthritis.
Tag	hFc
Products description	Anti-Canine HABP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine Hyaluronic Acid-Binding Protein (cHABP) emerges as a fundamental player in the intricate world of canine physiology. This glycoprotein, encoded by the cHABP gene, specializes in the orchestration of hyaluronic acid (HA), a prominent constituent of the extracellular matrix. HA's primary role is to maintain tissue hydration, lubrication, and resilience, and cHABP is its faithful guardian in the canine body. HA, a high molecular weight polysaccharide, resides in various tissues in dogs, including connective tissues, skin, and synovial fluid. Its biophysical properties make it a vital component for proper joint function and overall tissue health. However, HA is prone to degradation and requires constant vigilance to maintain its integrity. This is where cHABP steps in. cHABP forms tight bonds with HA molecules, effectively shielding them from enzymatic degradation and environmental factors. The significance of cHABP becomes particularly evident in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating smooth articulation and reducing friction during movement. Without adequate HA levels and efficient HA-binding proteins like cHABP, joints may become susceptible to wear and tear, leading to conditions like osteoarthritis, a painful and debilitating ailment in dogs. Moreover, cHABP's role extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. In doing so, it supports overall tissue integrity, wound healing, and the body's ability to withstand mechanical stress. Furthermore, cHABP interacts with other proteins and participates in various signaling pathways, influencing processes like tissue repair and inflammation.

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