Canine H-FABP antibody and antigen (recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-H-FABP-Ag01	Recombinant Canine H-FABP protein	3090
GMP-CAN-H-FABP-Ab01	Anti-Canine H-FABP mouse monoclonal antibody (mAb)	1953
GMP-CAN-H-FABP-Ab02	Anti-Canine H-FABP mouse monoclonal antibody (mAb)	1953
GMP-CAN-H-FABP-Ab03	Anti-Canine H-FABP human monoclonal antibody (mAb)	1953
GMP-CAN-H-FABP-Ab04	Anti-Canine H-FABP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-H-FABP-Ag01
Product Name	Recombinant Canine H-FABP protein
Target/Biomarker	Canine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Heart-type Fatty Acid-Binding Protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in H-FABP level test of animal Dog/Canine with myocardial injury.
Tag	His
Products description	Recombinant Canine H-FABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-H-FABP-Ab01, GMP-CAN-H-FABP-Ab02
Product Name	Anti-Canine H-FABP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Heart-type Fatty Acid-Binding Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies in H-FABP level test of animal Dog/Canine with myocardial injury.
Tag	mFc
Products description	Anti-Canine H-FABP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-H-FABP-Ab03, GMP-CAN-H-FABP-Ab04
Product Name	Anti-Canine H-FABP human monoclonal antibody (mAb)
Target/Biomarker	Canine Heart-type Fatty Acid-Binding Protein (H-FABP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Heart-type Fatty Acid-Binding Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies in H-FABP level test of animal Dog/Canine with myocardial injury.
Tag	hFc
Products description	Anti-Canine H-FABP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-H-FABP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

H-FABP, short for Heart-Fatty Acid Binding Protein, stands as a remarkable biomarker within the realm of canine biology. This small yet pivotal protein is predominantly expressed in the heart muscle of dogs (canines) and is intricately involved in the orchestration of fatty acid metabolism within cardiomyocytes. Structurally, H-FABP is a cytoplasmic protein with a distinct binding pocket that allows it to shuttle fatty acids, an essential energy source, within cardiac muscle cells. The exclusive localization of H-FABP within the heart tissue underscores its importance in assessing cardiac health. Under normal physiological conditions, H-FABP levels in the bloodstream of dogs remain relatively low. However, its concentration can dramatically increase in response to cardiac stress or injury, making it an invaluable diagnostic tool for veterinarians and a source of valuable insights for pet owners. H-FABP's function in the heart is multifaceted. It participates in the uptake, transport, and utilization of fatty acids as an energy substrate during various physiological conditions, such as exercise or stress. However, its significance extends far beyond metabolic regulation. H-FABP's role as a biomarker becomes particularly evident when the heart encounters challenges. In situations where cardiac ischemia or infarction occurs, such as during a heart attack, the heart muscle undergoes a process of injury due to inadequate blood supply. This ischemic injury triggers the release of H-FABP into the bloodstream. Thus, elevated levels of H-FABP in a dog's blood can serve as an early indicator of myocardial damage, even before clinical symptoms manifest.

About GDU