Canine GDF-15 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-GDF-15-Ag01	Recombinant Canine GDF-15 protein	3090
GMP-CAN-GDF-15-Ab01	Anti-Canine GDF-15 mouse monoclonal antibody (mAb)	1953
GMP-CAN-GDF-15-Ab02	Anti-Canine GDF-15 mouse monoclonal antibody (mAb)	1953
GMP-CAN-GDF-15-Ab03	Anti-Canine GDF-15 human monoclonal antibody (mAb)	1953
GMP-CAN-GDF-15-Ab04	Anti-Canine GDF-15 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-GDF-15-Ag01
Product Name	Recombinant Canine GDF-15 protein
Target/Biomarker	Canine Growth differentiation factor-15 (GDF-15)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Growth differentiation factor-15 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of animal Dog/Canine with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	His
Products description	Recombinant Canine GDF-15 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-GDF-15-Ab01, GMP-CAN-GDF-15-Ab02
Product Name	Anti-Canine GDF-15 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Growth differentiation factor-15 (GDF-15)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Growth differentiation factor-15 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies in GDF-15 level test of animal Dog/Canine with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	mFc
Products description	Anti-Canine GDF-15 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-GDF-15-Ab03, GMP-CAN-GDF-15-Ab04
Product Name	Anti-Canine GDF-15 human monoclonal antibody (mAb)
Target/Biomarker	Canine Growth differentiation factor-15 (GDF-15)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Growth differentiation factor-15 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies in GDF-15 level test of animal Dog/Canine with pressure overload, myocardial infarction, heart failure, and atherosclerosis.
Tag	hFc
Products description	Anti-Canine GDF-15 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-GDF-15 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Growth Differentiation Factor 15 (GDF-15), known as macrophage inhibitory cytokine 1 (MIC-1), stands as a multifaceted protein biomarker within the intricate landscape of canine biology. It belongs to the transforming growth factor-beta (TGF-β) superfamily and is secreted by various cell types, including macrophages, cardiac myocytes, and adipocytes. Structurally, GDF-15 is a dimeric protein, with two subunits held together by disulfide bonds. GDF-15 is a versatile regulator of cellular processes in dogs. It is involved in modulating inflammation, controlling cell growth, and regulating apoptosis (programmed cell death). In response to various stimuli, including inflammatory signals and cellular stress, GDF-15 levels can increase significantly, reflecting its role as a sentinel of canine health.

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