Canine FSH antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-FSH-Ag01	Recombinant Canine FSH protein	3090
GMP-CAN-FSH-Ab01	Anti-Canine FSH mouse monoclonal antibody (mAb)	1953
GMP-CAN-FSH-Ab02	Anti-Canine FSH mouse monoclonal antibody (mAb)	1953
GMP-CAN-FSH-Ab03	Anti-Canine FSH human monoclonal antibody (mAb)	1953
GMP-CAN-FSH-Ab04	Anti-Canine FSH human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-FSH-Ag01
Product Name	Recombinant Canine FSH protein
Target/Biomarker	Canine follicle stimulating hormone (FSH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine follicle stimulating hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
Tag	His
Products description	Recombinant Canine FSH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-FSH-Ab01, GMP-CAN-FSH-Ab02
Product Name	Anti-Canine FSH mouse monoclonal antibody (mAb)
Target/Biomarker	Canine follicle stimulating hormone (FSH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine follicle stimulating hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FSH antibodies in FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
Tag	mFc
Products description	Anti-Canine FSH mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FSH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-FSH-Ab03, GMP-CAN-FSH-Ab04
Product Name	Anti-Canine FSH human monoclonal antibody (mAb)
Target/Biomarker	Canine follicle stimulating hormone (FSH)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine follicle stimulating hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FSH antibodies in FSH level test of animal Dog/Canine with hypergonadotrophic-hypogonadism and infertility.
Tag	hFc
Products description	Anti-Canine FSH human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-FSH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Follicle-Stimulating Hormone (FSH) in dogs, or canines, is a master regulator of reproductive processes, standing as a testament to the intricate choreography of hormonal signals that govern the fertility of these beloved animals. Structurally, FSH is a glycoprotein hormone, part of the gonadotropin family, and is synthesized and secreted by the anterior pituitary gland. In the female canine reproductive system, FSH plays a pivotal role in orchestrating the estrous cycle. It's the hormone responsible for nurturing the development of ovarian follicles, each housing an immature egg (oocyte). As FSH levels rise, it signals the ovaries to initiate the recruitment and growth of these follicles, a process known as folliculogenesis. FSH's influence extends further, as it primes these follicles for ovulation, a momentous event in the reproductive calendar of a female dog. The regulation of FSH secretion is a finely tuned process, subject to intricate feedback mechanisms. The secretion of sex hormones, such as estrogen and inhibin, exerts a dynamic influence on FSH release. This feedback system ensures the precise timing and intensity of FSH secretion, ensuring that follicular development and ovulation occur at the optimal moments within the estrous cycle. In the male canine reproductive system, FSH's role is no less significant. Spermatogenesis, the intricate process of sperm cell development, hinges on the stimulation provided by FSH. Within the testes, FSH acts on specialized cells called Sertoli cells. These cells provide the essential nurturing environment for developing sperm cells. Under FSH's influence, Sertoli cells create the ideal conditions for sperm maturation, fostering the production of functional and motile sperm. The dynamic interplay between FSH and other hormones, such as luteinizing hormone (LH), is critical for the synchronization of male and female reproductive processes. In essence, FSH represents the molecular conductor of the symphony of events that culminate in successful canine reproduction.

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