Canine D-Dimer antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-D-Dimer-Ag01	Recombinant Canine D-Dimer protein	3090
GMP-CAN-D-Dimer-Ab01	Anti-Canine D-Dimer mouse monoclonal antibody (mAb)	1953
GMP-CAN-D-Dimer-Ab02	Anti-Canine D-Dimer mouse monoclonal antibody (mAb)	1953
GMP-CAN-D-Dimer-Ab03	Anti-Canine D-Dimer human monoclonal antibody (mAb)	1953
GMP-CAN-D-Dimer-Ab04	Anti-Canine D-Dimer human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-D-Dimer-Ag01
Product Name	Recombinant Canine D-Dimer protein
Target/Biomarker	Canine D Dimer (D-Dimer)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine D Dimer antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	His
Products description	Recombinant Canine D-Dimer protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-D-Dimer-Ab01, GMP-CAN-D-Dimer-Ab02
Product Name	Anti-Canine D-Dimer mouse monoclonal antibody (mAb)
Target/Biomarker	Canine D Dimer (D-Dimer)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine D Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies in D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	mFc
Products description	Anti-Canine D-Dimer mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-D-Dimer-Ab03, GMP-CAN-D-Dimer-Ab04
Product Name	Anti-Canine D-Dimer human monoclonal antibody (mAb)
Target/Biomarker	Canine D Dimer (D-Dimer)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine D Dimer antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies in D-Dimer level test of animal Dog/Canine with Thrombosis, disseminated intravascular coagulation (DIC).
Tag	hFc
Products description	Anti-Canine D-Dimer human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-D-Dimer antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

D-Dimer, as a biomarker, holds a significant position in veterinary hematology and clinical diagnostics, particularly when it comes to the canine population. To delve into its intricacies, we must first understand the broader context of coagulation and fibrinolysis within a dog's circulatory system. In simple terms, D-Dimer is a small protein fragment that originates during the dissolution of fibrin clots. Fibrin, a critical component in blood clot formation, is a mesh-like protein structure that traps blood cells to stop bleeding when an injury occurs. However, maintaining a delicate balance in the coagulation process is vital. In dogs, as in humans, there are times when this balance can be disrupted, leading to excessive or inadequate blood clot formation. D-Dimer enters the picture when these fibrin clots break down, either naturally or due to medical interventions. It acts as a marker for this process, indicating the presence of ongoing or recent coagulation activity. To detect D-Dimer in a dog's blood, veterinarians use specialized laboratory tests. Elevated D-Dimer levels suggest that the balance of clot formation and dissolution may be skewed, necessitating further investigation.

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