Canine cystatin C antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CysC-Ag01	Recombinant Canine cystatin C protein	3090
GMP-CAN-CysC-Ab01	Anti-Canine cystatin C mouse monoclonal antibody (mAb)	1953
GMP-CAN-CysC-Ab02	Anti-Canine cystatin C mouse monoclonal antibody (mAb)	1953
GMP-CAN-CysC-Ab03	Anti-Canine cystatin C human monoclonal antibody (mAb)	1953
GMP-CAN-CysC-Ab04	Anti-Canine cystatin C human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CysC-Ag01
Product Name	Recombinant Canine cystatin C protein
Target/Biomarker	Canine cystatin C (CysC)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine cystatin C antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CysC level test of animal Dog/Canine with Hormone disorders.
Tag	His
Products description	Recombinant Canine cystatin C protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CysC-Ab01, GMP-CAN-CysC-Ab02
Product Name	Anti-Canine cystatin C mouse monoclonal antibody (mAb)
Target/Biomarker	Canine cystatin C (CysC)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CysC antibodies in CysC level test of animal Dog/Canine with Hormone disorders.
Tag	mFc
Products description	Anti-Canine cystatin C mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CysC antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CysC-Ab03, GMP-CAN-CysC-Ab04
Product Name	Anti-Canine cystatin C human monoclonal antibody (mAb)
Target/Biomarker	Canine cystatin C (CysC)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine cystatin C antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CysC antibodies in CysC level test of animal Dog/Canine with Hormone disorders.
Tag	hFc
Products description	Anti-Canine cystatin C human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CysC antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine CYSC, or Cystatin C, may be unassuming in size, but its significance in the landscape of canine health cannot be overstated. This unpretentious protein operates as a sentinel, a vigilant monitor of the intricate machinery within a dog's body, specifically, the renal system. Produced by nucleated cells throughout a dog's body at a constant rate, Canine CYSC finds its moment in the spotlight within the kidneys, where it plays a pivotal role in assessing renal health. Its journey begins with the glomeruli, the kidney's intricate filtration units. Here, Canine CYSC is freely filtered from the blood, representing the initial step in evaluating kidney function. After its passage through the glomeruli, Canine CYSC embarks on a voyage through the renal tubules, where it faces a fate determined by the kidneys' filtration efficiency. In healthy dogs, the majority of CYSC is reabsorbed and subsequently catabolized by the tubules. This process ensures that Canine CYSC levels in the bloodstream remain relatively stable, mirroring the efficiency of glomerular filtration. The beauty of Canine CYSC lies in its sensitivity and specificity as a biomarker for renal health. Unlike traditional markers such as creatinine, Canine CYSC is less influenced by factors like muscle mass or diet. Consequently, it offers a more accurate reflection of glomerular filtration rate (GFR), making it an indispensable tool for assessing kidney function in dogs. Canine CYSC's ability to detect subtle changes in renal function, especially in the early stages of kidney disease, makes it a crucial asset for veterinarians. Its role extends far beyond diagnosis; it is a herald of proactive healthcare. By measuring CYSC levels, veterinarians can identify renal issues in their nascent stages, enabling timely intervention and a higher likelihood of successful treatment.

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