Canine C-Reactive Protein (CRP) antibody and antigen (recombinant protein)

Diagnostic anti-Canine C-Reactive Protein (CRP) antibodies pairs and antigen for animal health (animal Dog/Canine Inflammatory diseases, infections) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-CAN-CRP-Ag01 Recombinant Canine C-Reactive Protein (CRP) protein 3090
GMP-CAN-CRP-Ab01 Anti-Canine C-Reactive Protein (CRP) mouse monoclonal antibody (mAb) 1953
GMP-CAN-CRP-Ab02 Anti-Canine C-Reactive Protein (CRP) mouse monoclonal antibody (mAb) 1953
GMP-CAN-CRP-Ab03 Anti-Canine C-Reactive Protein (CRP) human monoclonal antibody (mAb) 1953
GMP-CAN-CRP-Ab04 Anti-Canine C-Reactive Protein (CRP) human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-CAN-CRP-Ag01
Product Name Recombinant Canine C-Reactive Protein (CRP) protein
Target/Biomarker Canine C-Reactive Protein (CRP)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Canine C-Reactive Protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CRP level test of animal Dog/Canine with Inflammatory diseases, infections.
Tag His
Products description Recombinant Canine C-Reactive Protein (CRP) protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-CAN-CRP-Ab01, GMP-CAN-CRP-Ab02
Product Name Anti-Canine C-Reactive Protein (CRP) mouse monoclonal antibody (mAb)
Target/Biomarker Canine C-Reactive Protein (CRP)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Canine C-Reactive Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CRP antibodies in CRP level test of animal Dog/Canine with Inflammatory diseases, infections.
Tag mFc
Products description Anti-Canine C-Reactive Protein (CRP) mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CRP antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-CAN-CRP-Ab03, GMP-CAN-CRP-Ab04
Product Name Anti-Canine C-Reactive Protein (CRP) human monoclonal antibody (mAb)
Target/Biomarker Canine C-Reactive Protein (CRP)
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Canine C-Reactive Protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CRP antibodies in CRP level test of animal Dog/Canine with Inflammatory diseases, infections.
Tag hFc
Products description Anti-Canine C-Reactive Protein (CRP) human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-CRP antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    GeneMedi's anti-cCRP monoclonal antibodies achieve excellent performance in immunoassays.

    GeneMedi's monoclonal antibodies targeting cCRP (canine C-reactive protein) deliver outstanding performance across different immunoassay systems, ensuring high sensitivity and reliability for accurate cCRP detection. These antibodies are designed to support consistent and precise results, making them ideal for various diagnostic and research applications.

    CRP validation

    Click to Zoom

    Figure 1. GeneMedi’s GMP-CAN-CRP monoclonal antibodies exhibit superior performance in sandwich and direct ELISA assays.

    A.Calibration curve for natural cCRP antigen in the sandwich immunoassay.
    B.Canine CRP levels in serum samples from both inflammatory and healthy individuals were measured using antibody pairs in a sandwich immunoassay.
    C-D. Sandwich immunoassay was performed to compare PC (phosphocholine) and GMP-CAN-CRP-Ab01 as the capture antibody in the presence (C) and absence (D) of Ca2+.
    E.Presence of PC does not affect CRP detection in sandwich immunoassays.
    F.Detection of natural cCRP on a direct ELISA platform in the presence of Ca2+ or EDTA using GMP-CAN-CRP-Ab06.
    G.The optimal antibody pairs selected based on the immunoassay system.


    GeneMedi's anti-cCRP polyclonal antibodies and recombinant cCRP are suitable for use in the sandwich immunoassay system.

    GeneMedi supplies polyclonal antibodies that can be used for the development of cCRP immunoassay systems, as well as recombinant antigens suitable for the calibration of cCRP immunoassay reagents, both of which exhibit excellent performance in the sandwich immunoassay system.

    CRP validation

    Click to Zoom

    Figure 2. GeneMedi’s anti-cCRP polyclonal antibodies and recombinant cCRP show superior performance in sandwich ELISA assays.

    A.Calibration curves for recombinant cCRP using mAb-mAb (red) and pAb-mAb (green) antibody pairs in the sandwich immunoassay.
    B.Detection results of serum cCRP from normal and systemically inflamed dogs using two antibody pairs in a sandwich immunoassay.
    C.Calibration curves for natural and recombinant cCRP in a sandwich immunoassay.
    D.Titration curves for recombinant and natural cCRP in a sandwich immunoassay using PC as the capture molecule.

    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Serial number: 1. Dog/Canine CRP (C-reactive protein) is a vital biomarker present in the bloodstream of dogs. CRP is a protein synthesized by the liver in response to inflammation, infection, or tissue damage within the body. It serves as an indicator of the presence and severity of these conditions in canines. Dog/Canine CRP is specifically designed to measure the levels of C-reactive protein in dogs. With its high sensitivity, it can accurately detect even minute levels of inflammation or infection in canine patients. The test involves obtaining a small blood sample from the dog, which is then meticulously analyzed to determine the concentration of CRP present.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

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