Canine CNP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CNP-Ag01	Recombinant Canine CNP protein	3090
GMP-CAN-CNP-Ab01	Anti-Canine CNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-CNP-Ab02	Anti-Canine CNP mouse monoclonal antibody (mAb)	1953
GMP-CAN-CNP-Ab03	Anti-Canine CNP human monoclonal antibody (mAb)	1953
GMP-CAN-CNP-Ab04	Anti-Canine CNP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CNP-Ag01
Product Name	Recombinant Canine CNP protein
Target/Biomarker	Canine C-type natriuretic peptide (ACE2/hFc)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine C-type natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACE2/hFc level test of animal Dog/Canine with cardiovascular disease.
Tag	His
Products description	Recombinant Canine CNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CNP-Ab01, GMP-CAN-CNP-Ab02
Product Name	Anti-Canine CNP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine C-type natriuretic peptide (ACE2/hFc)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine C-type natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies in ACE2/hFc level test of animal Dog/Canine with cardiovascular disease.
Tag	mFc
Products description	Anti-Canine CNP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CNP-Ab03, GMP-CAN-CNP-Ab04
Product Name	Anti-Canine CNP human monoclonal antibody (mAb)
Target/Biomarker	Canine C-type natriuretic peptide (ACE2/hFc)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine C-type natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies in ACE2/hFc level test of animal Dog/Canine with cardiovascular disease.
Tag	hFc
Products description	Anti-Canine CNP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-ACE2/hFc antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

In dogs, CNP demonstrates diverse roles beyond its cardiovascular effects. Here are some additional perspectives on Canine CNP: a) Vascular Development: CNP plays a crucial role in vascular development and angiogenesis during embryonic development. It contributes to the formation of blood vessels by promoting endothelial cell proliferation, migration, and tube formation. b) Skeletal Growth: CNP is involved in regulating the growth and development of long bones through its effects on the growth plates. It modulates chondrocyte proliferation, differentiation, and matrix synthesis in the growth plates, influencing bone growth and skeletal development. c) Reproductive System: CNP has been identified in the reproductive tissues of dogs, including the ovaries and testes. It may play a role in follicular development, ovulation, and spermatogenesis, although further research is needed to fully understand its functions in the reproductive system. d) Stress Response: CNP levels can be influenced by stress and certain pathological conditions. Monitoring CNP in dogs exposed to stressful situations or experiencing conditions like heart disease can provide insights into the physiological responses to stress and pathological stress-related changes.

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