Canine CK-MB antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CK-MB-Ag01	Recombinant Canine CK-MB protein	3090
GMP-CAN-CK-MB-Ab01	Anti-Canine CK-MB mouse monoclonal antibody (mAb)	1953
GMP-CAN-CK-MB-Ab02	Anti-Canine CK-MB mouse monoclonal antibody (mAb)	1953
GMP-CAN-CK-MB-Ab03	Anti-Canine CK-MB human monoclonal antibody (mAb)	1953
GMP-CAN-CK-MB-Ab04	Anti-Canine CK-MB human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CK-MB-Ag01
Product Name	Recombinant Canine CK-MB protein
Target/Biomarker	Canine Creatine Kinase MB (A1M)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Creatine Kinase MB antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in A1M level test of animal Dog/Canine with Myocardial hypoxia.
Tag	His
Products description	Recombinant Canine CK-MB protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CK-MB-Ab01, GMP-CAN-CK-MB-Ab02
Product Name	Anti-Canine CK-MB mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Creatine Kinase MB (A1M)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Creatine Kinase MB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies in A1M level test of animal Dog/Canine with Myocardial hypoxia.
Tag	mFc
Products description	Anti-Canine CK-MB mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CK-MB-Ab03, GMP-CAN-CK-MB-Ab04
Product Name	Anti-Canine CK-MB human monoclonal antibody (mAb)
Target/Biomarker	Canine Creatine Kinase MB (A1M)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Creatine Kinase MB antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies in A1M level test of animal Dog/Canine with Myocardial hypoxia.
Tag	hFc
Products description	Anti-Canine CK-MB human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-A1M antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Creatine Kinase-MB (CK-MB) stands as a pivotal enzyme biomarker within the intricate landscape of canine cardiology. It represents a specialized subtype of the enzyme creatine kinase (CK), which plays a fundamental role in energy metabolism, particularly in tissues with high-energy demands, such as skeletal and cardiac muscle. In dogs, CK-MB takes on a specific significance due to its primary localization within cardiac muscle cells. It exists in multiple isoforms, with the cardiac isoform CK-MB being predominantly found in the heart. The unique presence of CK-MB in cardiac muscle makes it a reliable and specific marker for assessing myocardial health. When cardiac muscle undergoes injury or stress, CK-MB is released into the bloodstream, where it becomes quantifiable. This phenomenon forms the basis for the use of CK-MB as an indicator of myocardial damage in dogs. The measurement of CK-MB levels plays a vital role in diagnosing various cardiac conditions and monitoring the response to treatment.

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