Canine CBS antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CBS-Ag01	Recombinant Canine CBS protein	3090
GMP-CAN-CBS-Ab01	Anti-Canine CBS mouse monoclonal antibody (mAb)	1953
GMP-CAN-CBS-Ab02	Anti-Canine CBS mouse monoclonal antibody (mAb)	1953
GMP-CAN-CBS-Ab03	Anti-Canine CBS human monoclonal antibody (mAb)	1953
GMP-CAN-CBS-Ab04	Anti-Canine CBS human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CBS-Ag01
Product Name	Recombinant Canine CBS protein
Target/Biomarker	Canine cystathionine-β-synthase ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine cystathionine-β-synthase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Canine CBS protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CBS-Ab01, GMP-CAN-CBS-Ab02
Product Name	Anti-Canine CBS mouse monoclonal antibody (mAb)
Target/Biomarker	Canine cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Canine CBS mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CBS-Ab03, GMP-CAN-CBS-Ab04
Product Name	Anti-Canine CBS human monoclonal antibody (mAb)
Target/Biomarker	Canine cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Canine CBS human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine C-reactive Protein (cCRP) is a pivotal biomarker, central to the physiological response of dogs to inflammatory challenges. Structurally, it is a pentameric protein, composed of five identical subunits, each boasting a molecular mass of approximately 25 kDa. Its synthesis primarily occurs in the hepatocytes of the liver, induced by pro-inflammatory cytokines like interleukin-6 (IL-6). The central role of cCRP lies in its rapid response to inflammation, injury, or infection. Upon the detection of such triggers, the liver immediately initiates the production of cCRP, leading to a noticeable increase in its concentration within the bloodstream. This swift reaction makes cCRP an invaluable sentinel, capable of detecting even subtle changes in a dog's health. Beyond its structural and biosynthetic intricacies, cCRP actively participates in the canine immune response. It serves as an acute-phase protein, facilitating the orchestration of the immune system's innate arm. cCRP augments the complement cascade, promoting opsonization and phagocytosis, thus bolstering the body's defenses against invading pathogens.

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