Canine CA50 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CA50-Ag01	Recombinant Canine CA50 protein	3090
GMP-CAN-CA50-Ab01	Anti-Canine CA50 mouse monoclonal antibody (mAb)	1953
GMP-CAN-CA50-Ab02	Anti-Canine CA50 mouse monoclonal antibody (mAb)	1953
GMP-CAN-CA50-Ab03	Anti-Canine CA50 human monoclonal antibody (mAb)	1953
GMP-CAN-CA50-Ab04	Anti-Canine CA50 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CA50-Ag01
Product Name	Recombinant Canine CA50 protein
Target/Biomarker	Canine Carbohydrate Antigen 50 (AIV-A H9N2 subtype)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Carbohydrate Antigen 50 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AIV-A H9N2 subtype level test of animal Dog/Canine with pancreatic and colorectal cancer.
Tag	His
Products description	Recombinant Canine CA50 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CA50-Ab01, GMP-CAN-CA50-Ab02
Product Name	Anti-Canine CA50 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Carbohydrate Antigen 50 (AIV-A H9N2 subtype)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Carbohydrate Antigen 50 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H9N2 subtype antibodies in AIV-A H9N2 subtype level test of animal Dog/Canine with pancreatic and colorectal cancer.
Tag	mFc
Products description	Anti-Canine CA50 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H9N2 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CA50-Ab03, GMP-CAN-CA50-Ab04
Product Name	Anti-Canine CA50 human monoclonal antibody (mAb)
Target/Biomarker	Canine Carbohydrate Antigen 50 (AIV-A H9N2 subtype)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Carbohydrate Antigen 50 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H9N2 subtype antibodies in AIV-A H9N2 subtype level test of animal Dog/Canine with pancreatic and colorectal cancer.
Tag	hFc
Products description	Anti-Canine CA50 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H9N2 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Carbohydrate Antigen 50 (CA50) is a glycoprotein biomarker with vital implications in canine health, particularly in the sphere of cancer diagnosis and monitoring. This biomarker is associated with several types of cancer in dogs, with a significant focus on those affecting the gastrointestinal and pancreatic regions. Structurally, CA50 is classified as a carbohydrate antigen, featuring a protein core with attached carbohydrate molecules. In the context of canine health, CA50 assumes significance as a diagnostic tool for the early detection of cancer. Cancers affecting the gastrointestinal and pancreatic regions can be insidious, often presenting with subtle or nonspecific clinical signs. CA50 blood tests offer a non-invasive and highly sensitive means of identifying these malignancies, enabling prompt intervention and potentially improving treatment outcomes. CA50 levels in a dog's bloodstream become elevated when cancer cells, particularly those found in gastrointestinal and pancreatic cancers, produce and release this glycoprotein. As a result, CA50 serves as a biomarker that can be readily detected and quantified through blood tests.

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