Canine CA-724 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-CA-724-Ag01	Recombinant Canine CA-724 protein	3090
GMP-CAN-CA-724-Ab01	Anti-Canine CA-724 mouse monoclonal antibody (mAb)	1953
GMP-CAN-CA-724-Ab02	Anti-Canine CA-724 mouse monoclonal antibody (mAb)	1953
GMP-CAN-CA-724-Ab03	Anti-Canine CA-724 human monoclonal antibody (mAb)	1953
GMP-CAN-CA-724-Ab04	Anti-Canine CA-724 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-CA-724-Ag01
Product Name	Recombinant Canine CA-724 protein
Target/Biomarker	Canine Cancer Antigen 72-4 (AIV-A N8 subtype)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Cancer Antigen 72-4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AIV-A N8 subtype level test of animal Dog/Canine with carcinomas of pancreas, stomach, gallbladder, colon, ovaries, cervix and endometrium.
Tag	His
Products description	Recombinant Canine CA-724 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CA-724-Ab01, GMP-CAN-CA-724-Ab02
Product Name	Anti-Canine CA-724 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Cancer Antigen 72-4 (AIV-A N8 subtype)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Cancer Antigen 72-4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A N8 subtype antibodies in AIV-A N8 subtype level test of animal Dog/Canine with carcinomas of pancreas, stomach, gallbladder, colon, ovaries, cervix and endometrium.
Tag	mFc
Products description	Anti-Canine CA-724 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A N8 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-CA-724-Ab03, GMP-CAN-CA-724-Ab04
Product Name	Anti-Canine CA-724 human monoclonal antibody (mAb)
Target/Biomarker	Canine Cancer Antigen 72-4 (AIV-A N8 subtype)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Cancer Antigen 72-4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A N8 subtype antibodies in AIV-A N8 subtype level test of animal Dog/Canine with carcinomas of pancreas, stomach, gallbladder, colon, ovaries, cervix and endometrium.
Tag	hFc
Products description	Anti-Canine CA-724 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A N8 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

CA-724, scientifically known as canine cancer antigen 724, is a biomarker of great importance in veterinary medicine, specifically in the realm of canine oncology. This biomarker is a glycoprotein, a protein molecule with carbohydrate chains attached, and it can be found in the bloodstream of dogs. What makes CA-724 particularly noteworthy is its association with various forms of cancer that affect dogs. In essence, CA-724 is a molecular signal that serves as a red flag for potential malignancies in dogs. It has been extensively studied and identified as a valuable indicator for diseases such as lymphoma, osteosarcoma, and mammary gland tumors in canine patients. When the levels of CA-724 are elevated in a dog's blood serum, it signals the possibility of cancer development or progression. Understanding CA-724's significance in canine health is critical for timely intervention and treatment. By detecting elevated CA-724 levels, veterinarians can identify the presence of cancer at an early stage, often before clinical symptoms manifest. This early detection is crucial as it allows for the prompt initiation of appropriate therapeutic measures, which can significantly improve the prognosis and quality of life for affected dogs.

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