Canine C-Peptide antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-C-Peptide-Ag01	Recombinant Canine C-Peptide protein	3090
GMP-CAN-C-Peptide-Ab01	Anti-Canine C-Peptide mouse monoclonal antibody (mAb)	1953
GMP-CAN-C-Peptide-Ab02	Anti-Canine C-Peptide mouse monoclonal antibody (mAb)	1953
GMP-CAN-C-Peptide-Ab03	Anti-Canine C-Peptide human monoclonal antibody (mAb)	1953
GMP-CAN-C-Peptide-Ab04	Anti-Canine C-Peptide human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-C-Peptide-Ag01
Product Name	Recombinant Canine C-Peptide protein
Target/Biomarker	Canine C-peptide (C-Peptide)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine C-peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
Tag	His
Products description	Recombinant Canine C-Peptide protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-C-Peptide-Ab01, GMP-CAN-C-Peptide-Ab02
Product Name	Anti-Canine C-Peptide mouse monoclonal antibody (mAb)
Target/Biomarker	Canine C-peptide (C-Peptide)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine C-peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-C-Peptide antibodies in C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
Tag	mFc
Products description	Anti-Canine C-Peptide mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-C-Peptide antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-C-Peptide-Ab03, GMP-CAN-C-Peptide-Ab04
Product Name	Anti-Canine C-Peptide human monoclonal antibody (mAb)
Target/Biomarker	Canine C-peptide (C-Peptide)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine C-peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-C-Peptide antibodies in C-Peptide level test of animal Dog/Canine with type 1 diabetes mellitus.
Tag	hFc
Products description	Anti-Canine C-Peptide human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-C-Peptide antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine C-Peptide, a molecular marvel of 31 amino acids, is intricately woven into the fabric of dogs' metabolic harmony. This peptide is the result of the proteolytic cleavage of proinsulin during its conversion into active insulin. While insulin takes center stage in glucose regulation, C-Peptide quietly plays its role as a companion biomarker, co-secreted alongside insulin by the pancreas. Canine C-Peptide emerges as a sentinel of pancreatic health and insulin production. It mirrors the natural ebb and flow of endogenous insulin secretion, pulsing into circulation in response to rising blood glucose levels. Unlike exogenously administered insulin, which is uniform and continuous, C-Peptide levels follow a distinct pattern that mimics the body's physiological insulin release. This pattern offers a unique window into the functioning of the pancreas, enabling veterinarians to assess the organ's ability to produce insulin. Furthermore, Canine C-Peptide serves as a linchpin in the diagnosis and differentiation of diabetes in dogs. It distinguishes between Type 1 and Type 2 diabetes, two distinct entities in the spectrum of canine diabetes. In Type 1 diabetes, C-Peptide levels are typically low or undetectable, signifying the autoimmune destruction of pancreatic beta cells and the absence of endogenous insulin production. In Type 2 diabetes, C-Peptide levels vary, reflecting the interplay of insulin resistance and impaired insulin secretion. This differentiation is pivotal, as it dictates treatment strategies and guides veterinarians in providing tailored care for dogs.

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