Canine AQP4 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-AQP4-Ag01	Recombinant Canine AQP4 protein	3090
GMP-CAN-AQP4-Ab01	Anti-Canine AQP4 mouse monoclonal antibody (mAb)	1953
GMP-CAN-AQP4-Ab02	Anti-Canine AQP4 mouse monoclonal antibody (mAb)	1953
GMP-CAN-AQP4-Ab03	Anti-Canine AQP4 human monoclonal antibody (mAb)	1953
GMP-CAN-AQP4-Ab04	Anti-Canine AQP4 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-AQP4-Ag01
Product Name	Recombinant Canine AQP4 protein
Target/Biomarker	Canine aquaporin-4 ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine aquaporin-4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with Cerebrovascular diseases.
Tag	His
Products description	Recombinant Canine AQP4 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AQP4-Ab01, GMP-CAN-AQP4-Ab02
Product Name	Anti-Canine AQP4 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine aquaporin-4 ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine aquaporin-4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with Cerebrovascular diseases.
Tag	mFc
Products description	Anti-Canine AQP4 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AQP4-Ab03, GMP-CAN-AQP4-Ab04
Product Name	Anti-Canine AQP4 human monoclonal antibody (mAb)
Target/Biomarker	Canine aquaporin-4 ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine aquaporin-4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with Cerebrovascular diseases.
Tag	hFc
Products description	Anti-Canine AQP4 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

AQP4, or Aquaporin 4, represents a remarkable feat of molecular engineering within the context of dogs (canines). This transmembrane protein is a member of the aquaporin family, a group of water channel proteins that facilitate the movement of water molecules across cell membranes. In canines, AQP4 assumes a prominent role in the central nervous system, where its strategic placement and function are indispensable for maintaining brain and spinal cord homeostasis. Structurally, AQP4 is a hexameric protein with six transmembrane domains and five connecting loops, forming a pore-like structure through which water molecules selectively pass. This high specificity for water ensures rapid and efficient water transport while preventing the movement of ions and other solutes. AQP4's localization within astrocytes, specialized glial cells in the brain and spinal cord, underscores its significance in regulating water balance within these crucial neural structures.

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