Canine ANP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-ANP-Ag01	Recombinant Canine ANP protein	3090
GMP-CAN-ANP-Ab01	Anti-Canine ANP mouse monoclonal antibody (mAb)	1953
GMP-CAN-ANP-Ab02	Anti-Canine ANP mouse monoclonal antibody (mAb)	1953
GMP-CAN-ANP-Ab03	Anti-Canine ANP human monoclonal antibody (mAb)	1953
GMP-CAN-ANP-Ab04	Anti-Canine ANP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-ANP-Ag01
Product Name	Recombinant Canine ANP protein
Target/Biomarker	Canine atrial natriuretic peptide ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine atrial natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with hypertension, cardiac hypertrophy and heart failure.
Tag	His
Products description	Recombinant Canine ANP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-ANP-Ab01, GMP-CAN-ANP-Ab02
Product Name	Anti-Canine ANP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine atrial natriuretic peptide ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine atrial natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with hypertension, cardiac hypertrophy and heart failure.
Tag	mFc
Products description	Anti-Canine ANP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-ANP-Ab03, GMP-CAN-ANP-Ab04
Product Name	Anti-Canine ANP human monoclonal antibody (mAb)
Target/Biomarker	Canine atrial natriuretic peptide ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine atrial natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with hypertension, cardiac hypertrophy and heart failure.
Tag	hFc
Products description	Anti-Canine ANP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

In dogs, ANP demonstrates diverse roles beyond its cardiovascular effects. Here are some additional perspectives on Canine ANP: a) Renal Function: ANP plays a crucial role in regulating renal blood flow and glomerular filtration rate in dogs. It helps maintain fluid and electrolyte balance by promoting sodium excretion, which affects renal function and overall fluid balance in the body. b) Adrenal Gland Regulation: ANP influences adrenal gland function in dogs. It suppresses the release of aldosterone, a hormone produced by the adrenal glands that promotes sodium reabsorption in the kidneys. By inhibiting aldosterone release, ANP contributes to sodium excretion and helps maintain electrolyte homeostasis. c) Inflammatory Responses: ANP has immunomodulatory properties and can affect inflammatory responses in dogs. It may regulate the production and release of pro-inflammatory cytokines, which play a role in various inflammatory conditions. Understanding ANP's involvement in inflammatory processes is relevant for studies on immune-related diseases in dogs. d) Exercise Physiology: ANP levels can transiently increase during exercise in dogs. This response is part of the body's adaptation to increased physical activity and helps regulate blood pressure and fluid balance during exercise. Monitoring ANP levels in dogs during exercise studies can provide insights into cardiovascular responses and endurance capacity.

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