Canine AFP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-AFP-Ag01	Recombinant Canine AFP protein	3090
GMP-CAN-AFP-Ab01	Anti-Canine AFP mouse monoclonal antibody (mAb)	1953
GMP-CAN-AFP-Ab02	Anti-Canine AFP mouse monoclonal antibody (mAb)	1953
GMP-CAN-AFP-Ab03	Anti-Canine AFP human monoclonal antibody (mAb)	1953
GMP-CAN-AFP-Ab04	Anti-Canine AFP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-AFP-Ag01
Product Name	Recombinant Canine AFP protein
Target/Biomarker	Canine Alpha-fetoprotein (AFP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine Alpha-fetoprotein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AFP level test of animal Dog/Canine with liver cancer, cancer of the ovaries or testicles, liver cirrhosis and hepatitis.
Tag	His
Products description	Recombinant Canine AFP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AFP-Ab01, GMP-CAN-AFP-Ab02
Product Name	Anti-Canine AFP mouse monoclonal antibody (mAb)
Target/Biomarker	Canine Alpha-fetoprotein (AFP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine Alpha-fetoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AFP antibodies in AFP level test of animal Dog/Canine with liver cancer, cancer of the ovaries or testicles, liver cirrhosis and hepatitis.
Tag	mFc
Products description	Anti-Canine AFP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AFP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AFP-Ab03, GMP-CAN-AFP-Ab04
Product Name	Anti-Canine AFP human monoclonal antibody (mAb)
Target/Biomarker	Canine Alpha-fetoprotein (AFP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine Alpha-fetoprotein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AFP antibodies in AFP level test of animal Dog/Canine with liver cancer, cancer of the ovaries or testicles, liver cirrhosis and hepatitis.
Tag	hFc
Products description	Anti-Canine AFP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AFP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Alpha-Fetoprotein (AFP) is a glycoprotein biomarker of significant importance in dogs (canines), playing distinct roles in fetal development and adult health. During fetal development, AFP is predominantly synthesized by the fetal liver and yolk sac. Its primary function is to serve as a carrier protein, facilitating the transport of essential nutrients, such as fatty acids, to the developing fetus. This supports fetal growth and organ development, with a particular emphasis on the liver. In healthy adult dogs, AFP levels are typically very low. The decline in AFP production occurs shortly after birth, as the yolk sac and fetal liver are replaced by the adult liver. However, deviations from this normal pattern can occur in response to specific pathological conditions.

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