Canine ACRV1 antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-CAN-ACRV1-Ag01	Recombinant Canine ACRV1 protein	3090
GMP-CAN-ACRV1-Ab01	Anti-Canine ACRV1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-ACRV1-Ab02	Anti-Canine ACRV1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-ACRV1-Ab03	Anti-Canine ACRV1 mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-CAN-ACRV1-Ab04	Anti-Canine ACRV1 mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-CAN-ACRV1-Ag01
Product Name	Recombinant Canine ACRV1 protein
Target/Biomarker	Canine acrosome protein (ACRV1)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine acrosome protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACRV1 level test of animal Dog/Canine with Fertilization.
Tag	His
Products description	Recombinant Canine ACRV1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-ACRV1-Ab01, GMP-CAN-ACRV1-Ab02, GMP-CAN-ACRV1-Ab03, GMP-CAN-ACRV1-Ab04
Product Name	Anti-Canine ACRV1 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine acrosome protein (ACRV1)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Anti-Canine acrosome protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ACRV1 level test of animal Dog/Canine with Fertilization.
Tag	mFc
Products description	Anti-Canine ACRV1 mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Canine ACRV1, or Acrosome Protein ACRV1, represents a linchpin in the intricate machinery of canine reproduction. This protein, primarily housed within the acrosome, a specialized organelle that crowns the head of mature sperm, holds the key to one of life's most critical processes—fertilization. Structurally, ACRV1 is a glycoprotein integral to the acrosome's composition. The acrosome is a sac-like structure containing enzymes and proteins crucial for sperm-egg interaction and penetration. ACRV1's role begins at the moment of sperm-egg contact, where it participates in sperm-egg binding and membrane fusion. These initial steps set the stage for the subsequent acrosomal reaction. The acrosomal reaction, orchestrated in part by ACRV1, is a cascade of events that unfolds as the sperm approaches the egg. It entails the release of acrosomal enzymes that digest the zona pellucida, a glycoprotein-rich layer surrounding the egg. ACRV1 contributes to the breakdown of the zona pellucida, facilitating the penetration of the egg's protective layers. Furthermore, ACRV1's function is not limited to the moment of fertilization. It is believed to play a role in the formation and maintenance of the acrosome itself. A well-formed and intact acrosome is vital for sperm function, and disruptions in ACRV1 expression or function can affect the acrosome's structural integrity.

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