Canine Aβ42 antibody and antigen (recombinant protein)

Diagnostic anti-Canine Aβ42 antibodies pairs and antigen for animal health (animal Dog/Canine Alzheimer Disease(AD)) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-CAN-AB42-Ag01 Recombinant Canine Aβ42 protein 3090
GMP-CAN-AB42-Ab01 Anti-Canine Aβ42 mouse monoclonal antibody (mAb) 1953
GMP-CAN-AB42-Ab02 Anti-Canine Aβ42 mouse monoclonal antibody (mAb) 1953
GMP-CAN-AB42-Ab03 Anti-Canine Aβ42 human monoclonal antibody (mAb) 1953
GMP-CAN-AB42-Ab04 Anti-Canine Aβ42 human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-CAN-AB42-Ag01
Product Name Recombinant Canine Aβ42 protein
Target/Biomarker Canine beta-amyloid 42 ()
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Canine beta-amyloid 42 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag His
Products description Recombinant Canine Aβ42 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-CAN-AB42-Ab01, GMP-CAN-AB42-Ab02
Product Name Anti-Canine Aβ42 mouse monoclonal antibody (mAb)
Target/Biomarker Canine beta-amyloid 42 ()
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Canine beta-amyloid 42 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag mFc
Products description Anti-Canine Aβ42 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-CAN-AB42-Ab03, GMP-CAN-AB42-Ab04
Product Name Anti-Canine Aβ42 human monoclonal antibody (mAb)
Target/Biomarker Canine beta-amyloid 42 ()
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Canine beta-amyloid 42 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag hFc
Products description Anti-Canine Aβ42 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Measuring Canine Aβ42 levels is paramount in veterinary medicine and neuroscience. Aβ42 has emerged as a critical biomarker due to its direct involvement in the pathogenesis of neurodegenerative diseases in dogs. Elevated Aβ42 levels have been correlated with the severity of cognitive dysfunction in dogs. By quantifying Aβ42 in cerebrospinal fluid or brain tissue, veterinarians and researchers can gauge the extent of amyloid plaque formation and the associated neurotoxicity. This not only aids in early diagnosis but also offers an objective means of monitoring disease progression. Beyond diagnosis, Aβ42 measurements play a pivotal role in preclinical research and drug development. They provide a quantifiable endpoint for evaluating the effectiveness of potential therapeutic interventions. Whether it's the development of disease-modifying drugs or strategies to enhance cognitive function in dogs, Aβ42 serves as a crucial indicator of treatment efficacy.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

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