Canine Aβ38 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-CAN-AB38-Ag01	Recombinant Canine Aβ38 protein	3090
GMP-CAN-AB38-Ab01	Anti-Canine Aβ38 mouse monoclonal antibody (mAb)	1953
GMP-CAN-AB38-Ab02	Anti-Canine Aβ38 mouse monoclonal antibody (mAb)	1953
GMP-CAN-AB38-Ab03	Anti-Canine Aβ38 human monoclonal antibody (mAb)	1953
GMP-CAN-AB38-Ab04	Anti-Canine Aβ38 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-CAN-AB38-Ag01
Product Name	Recombinant Canine Aβ38 protein
Target/Biomarker	Canine beta-amyloid 38 (AIV-A H3N2 subtype)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Canine beta-amyloid 38 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AIV-A H3N2 subtype level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Canine Aβ38 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AB38-Ab01, GMP-CAN-AB38-Ab02
Product Name	Anti-Canine Aβ38 mouse monoclonal antibody (mAb)
Target/Biomarker	Canine beta-amyloid 38 (AIV-A H3N2 subtype)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Canine beta-amyloid 38 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H3N2 subtype antibodies in AIV-A H3N2 subtype level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Canine Aβ38 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H3N2 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-CAN-AB38-Ab03, GMP-CAN-AB38-Ab04
Product Name	Anti-Canine Aβ38 human monoclonal antibody (mAb)
Target/Biomarker	Canine beta-amyloid 38 (AIV-A H3N2 subtype)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Canine beta-amyloid 38 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H3N2 subtype antibodies in AIV-A H3N2 subtype level test of animal Dog/Canine with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Canine Aβ38 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-AIV-A H3N2 subtype antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Canine Aβ38, also known as Amyloid Beta 38, emerges as a pivotal biomarker within the intricate realm of canine cognitive health. This unassuming peptide, a fragment of the amyloid precursor protein (APP), takes center stage in the unfolding drama of cognitive decline in aging dogs. Structurally related to the broader family of amyloid beta peptides, Aβ38 plays a central role in the formation of amyloid plaques within the canine brain, a hallmark of neurodegenerative conditions like canine cognitive dysfunction (CCD). In the complex milieu of the canine central nervous system, Aβ38's story unfolds. It is involved in the generation of amyloid plaques that can accumulate over time, gradually compromising cognitive function and behavior in dogs. CCD, akin to human dementia, casts a shadow on the twilight years of aging canine companions, affecting memory, spatial awareness, and overall cognitive abilities. Understanding Canine Aβ38 is akin to deciphering a critical chapter in the narrative of canine cognitive health. Its presence and levels in the brain offer insights into the progression of neurodegenerative processes in dogs, guiding our comprehension of CCD and related conditions. Monitoring Aβ38 levels equips researchers and veterinarians with a lens through which to observe the course of cognitive decline, helping to unlock potential interventions and therapies aimed at enhancing the quality of life for aging dogs.

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