Bovine p-tau202 and 205 antibody and antigen (recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-p-tau202-205-Ag01	Recombinant Bovine p-tau202 and 205 protein	3090
GMP-BOV-p-tau202-205-Ab01	Anti-Bovine p-tau202 and 205 mouse monoclonal antibody (mAb)	1953
GMP-BOV-p-tau202-205-Ab02	Anti-Bovine p-tau202 and 205 mouse monoclonal antibody (mAb)	1953
GMP-BOV-p-tau202-205-Ab03	Anti-Bovine p-tau202 and 205 human monoclonal antibody (mAb)	1953
GMP-BOV-p-tau202-205-Ab04	Anti-Bovine p-tau202 and 205 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-p-tau202-205-Ag01
Product Name	Recombinant Bovine p-tau202 and 205 protein
Target/Biomarker	Bovine Phospho-Tau202 And 205 (p-tau202 and 205)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Phospho-Tau202 And 205 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in p-tau202 and 205 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Bovine p-tau202 and 205 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-p-tau202-205-Ab01, GMP-BOV-p-tau202-205-Ab02
Product Name	Anti-Bovine p-tau202 and 205 mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Phospho-Tau202 And 205 (p-tau202 and 205)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Phospho-Tau202 And 205 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau202 and 205 antibodies in p-tau202 and 205 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Bovine p-tau202 and 205 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau202 and 205 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-p-tau202-205-Ab03, GMP-BOV-p-tau202-205-Ab04
Product Name	Anti-Bovine p-tau202 and 205 human monoclonal antibody (mAb)
Target/Biomarker	Bovine Phospho-Tau202 And 205 (p-tau202 and 205)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine Phospho-Tau202 And 205 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau202 and 205 antibodies in p-tau202 and 205 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Bovine p-tau202 and 205 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-p-tau202 and 205 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Associated products

Target/Biomarker information

Bovine p-tau202 and p-tau205, the phosphorylated Tau Proteins unique to cattle, represent a vital aspect of bovine neurobiology. At their core, they are Tau proteins that have undergone specific biochemical modifications – phosphorylation – at residues 202 and 205. Under normal circumstances, Tau proteins in cattle play a pivotal role in stabilizing microtubules, essential for axonal stability and intracellular transport within neuronal cells. However, in the context of neurodegenerative diseases, the narrative takes a different course. Phosphorylation events can trigger the misfolding and aggregation of Tau proteins, and in cattle, p-tau202 and p-tau205 tend to aggregate and form neurofibrillary tangles (NFTs) within neural tissues. These NFTs, akin to those observed in human neurodegenerative diseases like Alzheimer's, represent a pathological signature of various bovine neurodegenerative conditions. The accumulation of p-tau202 and p-tau205 in NFTs contributes to progressive neuronal dysfunction, altered behavior, and motor disturbances observed in conditions such as bovine spongiform encephalopathy (BSE) and other neurocognitive disorders in cattle.

About GDU