Bovine cTnI antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-cTnI-Ag01	Recombinant Bovine cTnI protein	3090
GMP-BOV-cTnI-Ab01	Anti-Bovine cTnI mouse monoclonal antibody (mAb)	1953
GMP-BOV-cTnI-Ab02	Anti-Bovine cTnI mouse monoclonal antibody (mAb)	1953
GMP-BOV-cTnI-Ab03	Anti-Bovine cTnI human monoclonal antibody (mAb)	1953
GMP-BOV-cTnI-Ab04	Anti-Bovine cTnI human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-cTnI-Ag01
Product Name	Recombinant Bovine cTnI protein
Target/Biomarker	Bovine Cardiac Troponin I (cTnI)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Cardiac Troponin I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cTnI level test of animal Bovines/Cattle with myocardial infarction.
Tag	His
Products description	Recombinant Bovine cTnI protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-cTnI-Ab01, GMP-BOV-cTnI-Ab02
Product Name	Anti-Bovine cTnI mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Cardiac Troponin I (cTnI)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Cardiac Troponin I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies in cTnI level test of animal Bovines/Cattle with myocardial infarction.
Tag	mFc
Products description	Anti-Bovine cTnI mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-cTnI-Ab03, GMP-BOV-cTnI-Ab04
Product Name	Anti-Bovine cTnI human monoclonal antibody (mAb)
Target/Biomarker	Bovine Cardiac Troponin I (cTnI)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine Cardiac Troponin I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies in cTnI level test of animal Bovines/Cattle with myocardial infarction.
Tag	hFc
Products description	Anti-Bovine cTnI human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-cTnI antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cardiac Troponin I (cTnI), a cardiac-specific biomarker, holds a position of utmost importance in bovine (cattle) physiology, particularly in the realm of cardiac health assessment. This protein, predominantly found in the bloodstream of cattle, serves as a critical indicator of cardiac well-being. To grasp the full significance of cTnI, it is imperative to delve into its structural attributes, functional role, and its profound implications in bovine cardiology. Structurally, cTnI is one of the three subunits of the troponin complex, the others being cardiac Troponin T (cTnT) and cardiac Troponin C (cTnC). This complex is strategically located within the sarcomeres of cardiac muscle fibers, where it exerts meticulous control over muscle contraction. The precision of this regulation is pivotal for the efficient pumping of blood by the bovine heart. What sets cTnI apart is its remarkable cardiac specificity. While other troponin isoforms exist in skeletal muscle, cTnI is exclusively expressed in the heart. This exclusivity makes cTnI an extraordinarily specific biomarker for assessing cardiac muscle injury or damage. When cardiac cells are compromised due to factors such as myocardial infarction, cardiac diseases, or cardiac trauma, cTnI is released into the bloodstream. Consequently, elevated levels of cTnI in a bovine's blood can serve as a critical diagnostic indicator of cardiac health. The detection of cTnI in cattle is typically accomplished through immunoassays, such as enzyme-linked immunosorbent assays (ELISA). These assays provide a quantitative measure of cTnI concentration, enabling veterinarians to evaluate the extent of cardiac injury or disease. The sensitivity of these assays is such that even minor myocardial damage can lead to detectable elevations in cTnI levels, enabling early diagnosis and intervention.

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