Bovine cIV antibody and antigen (recombinant protein)

Diagnostic anti-Bovine cIV antibodies pairs and antigen for animal health (animal Bovines/Cattle Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury.) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-BOV-cIV-Ag01 Recombinant Bovine cIV protein 3090
GMP-BOV-cIV-Ab01 Anti-Bovine cIV mouse monoclonal antibody (mAb) 1953
GMP-BOV-cIV-Ab02 Anti-Bovine cIV mouse monoclonal antibody (mAb) 1953
GMP-BOV-cIV-Ab03 Anti-Bovine cIV human monoclonal antibody (mAb) 1953
GMP-BOV-cIV-Ab04 Anti-Bovine cIV human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-BOV-cIV-Ag01
Product Name Recombinant Bovine cIV protein
Target/Biomarker Bovine collagen type IV ()
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Bovine collagen type IV antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag His
Products description Recombinant Bovine cIV protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-BOV-cIV-Ab01, GMP-BOV-cIV-Ab02
Product Name Anti-Bovine cIV mouse monoclonal antibody (mAb)
Target/Biomarker Bovine collagen type IV ()
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Bovine collagen type IV antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag mFc
Products description Anti-Bovine cIV mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-BOV-cIV-Ab03, GMP-BOV-cIV-Ab04
Product Name Anti-Bovine cIV human monoclonal antibody (mAb)
Target/Biomarker Bovine collagen type IV ()
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Bovine collagen type IV antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with Goodpasture syndrome, Alport syndrome, glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps. porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury..
Tag hFc
Products description Anti-Bovine cIV human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Bovine Cardiac Troponin I (cTnI) is a remarkable biomarker that takes center stage in the intricate choreography of bovine cardiac muscle contraction. As a species-specific protein found exclusively within the cardiac muscle of cattle, cTnI assumes a pivotal role in ensuring the rhythmic and effective pumping of blood through the bovine circulatory system. Structurally, cTnI forms part of the troponin complex, a trio of proteins that governs the contractile activity of muscle fibers. This complex includes cTnI (inhibitory subunit), cTnT (tropomyosin-binding subunit), and cTnC (calcium-binding subunit). Among these, cTnI is the conductor of the orchestra, orchestrating the symphony of cardiac muscle contraction. The core function of cTnI lies in its ability to regulate the interaction between actin and myosin—the two major proteins involved in muscle contraction. In the absence of calcium ions (Ca2+), cTnI binds to actin, effectively preventing the interaction between actin and myosin. This inhibition ensures that the heart remains relaxed and at rest when not pumping blood. However, when the heart receives the signal to contract, typically in response to an electrical impulse, calcium ions (Ca2+) flood into the cardiac muscle cell. This influx of Ca2+ induces a conformational change in cTnI, releasing its grip on actin. With this inhibitory hold released, actin and myosin can now interact, initiating the process of muscle contraction. This synchronized and highly regulated dance of proteins is what enables the bovine heart to contract efficiently, pumping blood to nourish vital organs and tissues.



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    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

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