Bovine YKL-40 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-YKL-40-Ag01	Recombinant Bovine YKL-40 protein	3090
GMP-BOV-YKL-40-Ab01	Anti-Bovine YKL-40 mouse monoclonal antibody (mAb)	1953
GMP-BOV-YKL-40-Ab02	Anti-Bovine YKL-40 mouse monoclonal antibody (mAb)	1953
GMP-BOV-YKL-40-Ab03	Anti-Bovine YKL-40 human monoclonal antibody (mAb)	1953
GMP-BOV-YKL-40-Ab04	Anti-Bovine YKL-40 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-YKL-40-Ag01
Product Name	Recombinant Bovine YKL-40 protein
Target/Biomarker	Bovine Chitinase-3-like protein 1 (YKL-40)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Chitinase-3-like protein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Bovine YKL-40 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-YKL-40-Ab01, GMP-BOV-YKL-40-Ab02
Product Name	Anti-Bovine YKL-40 mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Chitinase-3-like protein 1 (YKL-40)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Chitinase-3-like protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-YKL-40 antibodies in YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Bovine YKL-40 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-YKL-40 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-YKL-40-Ab03, GMP-BOV-YKL-40-Ab04
Product Name	Anti-Bovine YKL-40 human monoclonal antibody (mAb)
Target/Biomarker	Bovine Chitinase-3-like protein 1 (YKL-40)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine Chitinase-3-like protein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-YKL-40 antibodies in YKL-40 level test of animal Bovines/Cattle with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Bovine YKL-40 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-YKL-40 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Bovine YKL-40, a glycoprotein with a molecular weight of approximately 40 kDa, emerges as a captivating player in the intricate orchestra of bovine immune responses and tissue dynamics. While it shares structural features with chitinases, it stands apart by virtue of its absence of chitinase activity. Its presence is pervasive in various bovine tissues, with prominent expression in the liver, kidneys, lungs, and immune cells. Structurally, Bovine YKL-40 is characterized by its unique chitin-binding domain, which hints at its involvement in tissue remodeling and repair. The glycosylation of this protein enhances its stability and modulates its functions, particularly within the context of inflammation. The regulation of Bovine YKL-40 expression is meticulously orchestrated, with immune cells, including macrophages and neutrophils, being prominent sources. These cells respond to inflammatory signals by producing YKL-40, marking it as a pro-inflammatory mediator and a sentinel of immune system activation. Beyond its role in immune responses, Bovine YKL-40 is intricately linked to tissue remodeling processes. In conditions marked by tissue injury and repair, such as wound healing and fibrosis, YKL-40's interactions with fibroblasts and epithelial cells gain prominence. It appears to modulate cellular activities associated with extracellular matrix turnover and tissue restructuring.

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