Bovine VDBP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-VDBP-Ag01	Recombinant Bovine VDBP protein	3090
GMP-BOV-VDBP-Ab01	Anti-Bovine VDBP mouse monoclonal antibody (mAb)	1953
GMP-BOV-VDBP-Ab02	Anti-Bovine VDBP mouse monoclonal antibody (mAb)	1953
GMP-BOV-VDBP-Ab03	Anti-Bovine VDBP human monoclonal antibody (mAb)	1953
GMP-BOV-VDBP-Ab04	Anti-Bovine VDBP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-VDBP-Ag01
Product Name	Recombinant Bovine VDBP protein
Target/Biomarker	Bovine vitamin D binding protein (SPA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine vitamin D binding protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SPA level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
Tag	His
Products description	Recombinant Bovine VDBP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-VDBP-Ab01, GMP-BOV-VDBP-Ab02
Product Name	Anti-Bovine VDBP mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine vitamin D binding protein (SPA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine vitamin D binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies in SPA level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
Tag	mFc
Products description	Anti-Bovine VDBP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-VDBP-Ab03, GMP-BOV-VDBP-Ab04
Product Name	Anti-Bovine VDBP human monoclonal antibody (mAb)
Target/Biomarker	Bovine vitamin D binding protein (SPA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine vitamin D binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies in SPA level test of animal Bovines/Cattle with liver failure, type I diabetes, cystic fibrosis.
Tag	hFc
Products description	Anti-Bovine VDBP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SPA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Vitamin D-Binding Protein (VDBP) in cattle, or bovines, emerges as a multifunctional sentinel, standing at the crossroads of vitamin D metabolism and immune modulation within these robust animals. Structurally, VDBP is a glycoprotein, with a molecular weight of approximately 58-59 kDa, synthesized predominantly in the liver before embarking on its journey through the bloodstream. At the heart of VDBP's mission lies the transportation of vitamin D metabolites, with a primary emphasis on vitamin D3. Functioning as a carrier protein, VDBP binds to vitamin D and embarks on a journey that ensures its safe and efficient delivery to target tissues and cells throughout the bovine body. This meticulous oversight is crucial, as vitamin D is a linchpin in the regulation of calcium and phosphorus homeostasis, profoundly impacting bone health, muscle function, and an array of physiological processes fundamental to cattle well-being. The journey of vitamin D, under VDBP's vigilant guidance, involves a choreography of interactions with various tissues. It influences the intestinal absorption of calcium and phosphorus, vital for skeletal integrity and muscle contraction. Additionally, vitamin D plays a role in immune responses, cell proliferation, and differentiation, underscoring its significance as a regulator of both musculoskeletal and immune functions in cattle. However, VDBP's role transcends vitamin D transport; it extends into the domain of immunomodulation. VDBP exerts its influence on the immune system by interacting with immune cells, particularly macrophages. This interaction modulates immune responses, highlighting VDBP's role as a pivotal component of the bovine immune system. It acts as a bridge between vitamin D metabolism and immune functions, underscoring its multifaceted nature within the intricate framework of cattle physiology.

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