Bovine TrxR antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-TrxR-Ag01	Recombinant Bovine TrxR protein	3090
GMP-BOV-TrxR-Ab01	Anti-Bovine TrxR mouse monoclonal antibody (mAb)	1953
GMP-BOV-TrxR-Ab02	Anti-Bovine TrxR mouse monoclonal antibody (mAb)	1953
GMP-BOV-TrxR-Ab03	Anti-Bovine TrxR human monoclonal antibody (mAb)	1953
GMP-BOV-TrxR-Ab04	Anti-Bovine TrxR human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-TrxR-Ag01
Product Name	Recombinant Bovine TrxR protein
Target/Biomarker	Bovine thioredoxin reductase (SAA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine thioredoxin reductase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAA level test of animal Bovines/Cattle with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	His
Products description	Recombinant Bovine TrxR protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-TrxR-Ab01, GMP-BOV-TrxR-Ab02
Product Name	Anti-Bovine TrxR mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine thioredoxin reductase (SAA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Bovines/Cattle with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	mFc
Products description	Anti-Bovine TrxR mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-TrxR-Ab03, GMP-BOV-TrxR-Ab04
Product Name	Anti-Bovine TrxR human monoclonal antibody (mAb)
Target/Biomarker	Bovine thioredoxin reductase (SAA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Bovines/Cattle with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	hFc
Products description	Anti-Bovine TrxR human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Bovine Thioredoxin Reductase (TrxR) stands as a sentinel within the intricate cellular landscape of cattle. This selenium-dependent selenoprotein assumes the role of guardian, preserving the redox equilibrium upon which the health and vitality of cattle depend. Structurally, Bovine TrxR is a marvel of biological engineering, featuring a catalytic center brimming with the trace element selenium. This catalytic site is the epicenter of TrxR's mission: the reduction of oxidized thioredoxin, a pivotal antioxidant protein. In essence, Bovine TrxR serves as the restoration architect, ensuring that thioredoxin remains in its reduced, active form. This is a fundamental defense mechanism against the onslaught of reactive oxygen species (ROS), the natural byproducts of cellular metabolism that can wreak havoc on cellular structures. Bovine TrxR's journey begins with the recognition of oxidized thioredoxin, whose disulfide bonds are poised for reduction. TrxR employs its selenium-driven enzymatic prowess to orchestrate the reduction process, transforming thioredoxin into its active, protective state. This rejuvenation ensures that thioredoxin remains poised to combat ROS and maintain the intricate balance of cellular redox processes.

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