Bovine TIMP-1 antibody and antigen (recombinant protein)

Diagnostic anti-Bovine TIMP-1 antibodies pairs and antigen for animal health (animal Bovines/Cattle coronary artery stenosis, coronary artery lesions) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-BOV-TIMP-1-Ag01 Recombinant Bovine TIMP-1 protein 3090
GMP-BOV-TIMP-1-Ab01 Anti-Bovine TIMP-1 mouse monoclonal antibody (mAb) 1953
GMP-BOV-TIMP-1-Ab02 Anti-Bovine TIMP-1 mouse monoclonal antibody (mAb) 1953
GMP-BOV-TIMP-1-Ab03 Anti-Bovine TIMP-1 human monoclonal antibody (mAb) 1953
GMP-BOV-TIMP-1-Ab04 Anti-Bovine TIMP-1 human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-BOV-TIMP-1-Ag01
Product Name Recombinant Bovine TIMP-1 protein
Target/Biomarker Bovine Matrix Metalloproteinase Inhibitor-1 (S100-A9)
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Bovine Matrix Metalloproteinase Inhibitor-1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Bovines/Cattle with coronary artery stenosis, coronary artery lesions.
Tag His
Products description Recombinant Bovine TIMP-1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-BOV-TIMP-1-Ab01, GMP-BOV-TIMP-1-Ab02
Product Name Anti-Bovine TIMP-1 mouse monoclonal antibody (mAb)
Target/Biomarker Bovine Matrix Metalloproteinase Inhibitor-1 (S100-A9)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Bovine Matrix Metalloproteinase Inhibitor-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Bovines/Cattle with coronary artery stenosis, coronary artery lesions.
Tag mFc
Products description Anti-Bovine TIMP-1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-BOV-TIMP-1-Ab03, GMP-BOV-TIMP-1-Ab04
Product Name Anti-Bovine TIMP-1 human monoclonal antibody (mAb)
Target/Biomarker Bovine Matrix Metalloproteinase Inhibitor-1 (S100-A9)
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Recombinant Bovine Matrix Metalloproteinase Inhibitor-1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Bovines/Cattle with coronary artery stenosis, coronary artery lesions.
Tag hFc
Products description Anti-Bovine TIMP-1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    In cattle, TIMP-1 demonstrates multifaceted functions beyond its role as a metalloproteinase inhibitor. Extensive research has revealed its involvement in various physiological and pathophysiological processes. TIMP-1 is secreted by different cell types, including fibroblasts, synovial cells, and chondrocytes, and its expression can be regulated by factors such as mechanical stress, growth factors, and cytokines. TIMP-1 modulates the balance between extracellular matrix components, such as collagen, elastin, and proteoglycans, by inhibiting the activity of matrix metalloproteinases. This regulation is critical for maintaining tissue homeostasis, preventing excessive matrix degradation, and promoting proper tissue repair. Furthermore, TIMP-1 has been implicated in angiogenesis, the process of forming new blood vessels. It influences endothelial cell migration, proliferation, and tube formation, all of which are indispensable for the formation of functional vasculature during wound healing and tissue regeneration in cattle. Studies have also highlighted the role of TIMP-1 in immune response modulation. It exhibits immunomodulatory effects by influencing leukocyte migration, regulating cytokine production, and modulating the activity of immune cells. This aspect of TIMP-1 function contributes to its involvement in various inflammatory diseases and immune-mediated disorders in cattle.



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