Bovine Proinsulin antibody and antigen (recombinant protein)
Diagnostic anti-Bovine Proinsulin antibodies pairs and antigen for animal health (animal Bovines/Cattle type 2 diabetes) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT
Product information
Size: 1mg | 10mg | 100mg
Catalog No. | Description | US $ Price (per mg) | First Order Discount | First Order Discount Price |
---|---|---|---|---|
GMP-BOV-Proinsulin-Ag01 | Recombinant Bovine Proinsulin protein | 3090 | ||
GMP-BOV-Proinsulin-Ab01 | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) | 1953 | 20% | 1562.4 |
GMP-BOV-Proinsulin-Ab02 | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) | 1953 | 20% | 1562.4 |
GMP-BOV-Proinsulin-Ab03 | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) | 1953 | 20% | 1562.4 |
GMP-BOV-Proinsulin-Ab04 | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) | 1953 | 20% | 1562.4 |
Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)
Product Description
Cat No. of Products | GMP-BOV-Proinsulin-Ag01 |
Product Name | Recombinant Bovine Proinsulin protein |
Target/Biomarker | Bovine Proinsulin |
Expression platform | E.coli |
Isotypes | Recombinant Antigen |
Bioactivity validation | Anti-Bovine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with type 2 diabetes. |
Tag | His |
Products description | Recombinant Bovine Proinsulin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Products | GMP-BOV-Proinsulin-Ab01, GMP-BOV-Proinsulin-Ab02, GMP-BOV-Proinsulin-Ab03, GMP-BOV-Proinsulin-Ab04 |
Product Name | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) |
Target/Biomarker | Bovine Proinsulin |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Anti-Bovine Proinsulin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with type 2 diabetes. |
Tag | mFc |
Products description | Anti-Bovine Proinsulin mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker information
Bovine Proinsulin, an intricate 86-amino acid peptide hormone, occupies a pivotal position in the complex orchestra of insulin biosynthesis within cattle. It is synthesized and secreted by the beta cells nestled within the pancreatic islets of Langerhans, marking the initiation of insulin production. The journey of Cattle Proinsulin begins with the synthesis of preproinsulin, a larger precursor molecule. This preproinsulin subsequently undergoes a profound transformation, folding into proinsulin, a molecule comprising three distinct regions: the A chain, B chain, and a connecting peptide known as the C-peptide. The C-peptide, an integral component of proinsulin, is significant for its role in insulin biosynthesis. During proinsulin processing, a series of specific enzymes operate with precision to cleave the C-peptide from proinsulin. This cleavage event marks a critical transition, as it transforms proinsulin into the active insulin molecule. The newly formed insulin is then released into circulation, where it exerts its profound influence on glucose metabolism. The presence of the C-peptide within proinsulin is more than a structural element; it holds physiological significance. While it does not possess the same glucose-lowering properties as insulin, research suggests that the C-peptide may have independent actions on blood vessel health and other metabolic processes, making it a subject of scientific interest and exploration.
About GDU
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