Cow Pregnancy-associated glycoprotein 1 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-Preg-ass-gly-1-Ag01	Recombinant Cow Pregnancy-associated glycoprotein 1 protein	3090
GMP-BOV-Preg-ass-gly-1-Ab01	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	3090
GMP-BOV-Preg-ass-gly-1-Ab02	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)	3090
GMP-BOV-Preg-ass-gly-1-Ab03	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	3090
GMP-BOV-Preg-ass-gly-1-Ab04	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)	3090

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-Preg-ass-gly-1-Ag01
Product Name	Recombinant Cow Pregnancy-associated glycoprotein 1 protein
Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1 ()
Alias of Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Pregnancy-Associated Glycoprotein 1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with N/A.
Tag	His
Products description	Recombinant Cow Pregnancy-associated glycoprotein 1 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-Preg-ass-gly-1-Ab01, GMP-BOV-Preg-ass-gly-1-Ab02
Product Name	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1 ()
Alias of Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Pregnancy-Associated Glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with N/A.
Tag	mFc
Products description	Anti-Cow Pregnancy-associated glycoprotein 1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-Preg-ass-gly-1-Ab03, GMP-BOV-Preg-ass-gly-1-Ab04
Product Name	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb)
Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1 ()
Alias of Target/Biomarker	Bovine Pregnancy-Associated Glycoprotein 1
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine Pregnancy-Associated Glycoprotein 1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with N/A.
Tag	hFc
Products description	Anti-Cow Pregnancy-associated glycoprotein 1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Pregnancy-Associated Glycoprotein 1 (PAG-1) stands as a distinctive biomarker that exemplifies the intricacies of bovine reproduction. Produced exclusively during gestation in cattle (Bos taurus), PAG-1 belongs to the family of pregnancy-associated glycoproteins, a group of proteins that exhibit selective expression during pregnancy, setting them apart from non-pregnant states. The journey of PAG-1 commences with the successful implantation of the conceptus in the uterine wall. Placental cells, particularly binucleate trophoblast cells, undertake the synthesis and secretion of PAG-1. This specialized protein gradually finds its way into the maternal bloodstream, where its presence becomes detectable. Notably, PAG-1 is not just a single entity but represents a group of related proteins, each with distinct properties and roles within the context of bovine pregnancy. While the precise biological functions of PAG-1 are subjects of ongoing scientific exploration, it is believed to partake in immunomodulation, a crucial process that ensures the maternal immune system tolerates the presence of the developing fetus. PAG-1 is thought to contribute to the establishment of immunological tolerance, preventing the mother's immune system from recognizing the fetus as a foreign entity. This immunomodulatory function is vital for the success of pregnancy and the protection of the developing embryo and fetus from immune-mediated harm. Additionally, PAG-1 may play roles in placental development and nutrient transport. As pregnancy progresses, the placenta undergoes dynamic changes to support the growing fetus. PAG-1's involvement in these processes underscores its significance in the orchestration of bovine reproduction.

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