Bovine PA antibody and antigen (recombinant protein)

Diagnostic anti-Bovine PA antibodies pairs and antigen for animal health (animal Bovines/Cattle liver disease, inflammation, or tissue death) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-PA-Ag01Bovine PA$3090.00
GMP-BOV-PA-Ab01Anti-Bovine PA mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-PA-Ab02Anti-Bovine PA mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-PA-Ab03Anti-Bovine PA human monoclonal antibody (mAb)$3090.00
GMP-BOV-PA-Ab04Anti-Bovine PA human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-PA-Ag01
Product NameBovine PA
Target/BiomarkerBovine PA
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine PA antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
TagHis
Reconized/Reactive SpecicsBovine PA
Product descriptionRecombinant Bovine PA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-PA-Ab01,GMP-BOV-PA-Ab02
Target/BiomarkerBovine PA
Product NameAnti-Bovine PA mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PA antibodies in Bovine PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
Product descriptionAnti-Bovine PA mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PA antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-PA-Ab03,GMP-BOV-PA-Ab04
Target/BiomarkerBovine PA
Product NameAnti-Bovine PA human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine PA antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine PA antibodies in Bovine PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
Product descriptionAnti-Bovine PA mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine Prothrombin Activation Fragment 1+2 (cPAF1+2) stands as a pivotal biochemical entity within the intricate tapestry of bovine hemostasis. Structurally, it emerges as a fragment resulting from the activation of prothrombin (Factor II) into thrombin (Factor IIa) during the coagulation cascade—a process choreographed by a cascade of coagulation factors and platelet interactions. This activation event serves as the foundation of blood clot formation, a process that underpins the hemostatic equilibrium in cattle.

    Prothrombin, an unassuming precursor protein, circulates in the bovine bloodstream until it encounters vascular injury. When such an injury occurs, a meticulously orchestrated sequence of enzymatic reactions unfolds, culminating in the cleavage of prothrombin into two fragments: thrombin and cPAF1+2. Thrombin, the multifaceted enzyme generated through this process, assumes the central role in creating a stable blood clot. It catalyzes the conversion of soluble fibrinogen into insoluble fibrin strands, which provide the structural scaffold of a clot.

    In contrast, cPAF1+2 does not actively participate in clot formation but plays a pivotal role as a marker of ongoing thrombin generation within the bovine hemostatic system. Its presence in circulation serves as a dynamic reflection of the equilibrium between prothrombin activation and thrombin regulation, offering insights into the coagulation status of cattle.



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    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.