Bovine PA antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-PA-Ag01	Recombinant Bovine PA protein	3090
GMP-BOV-PA-Ab01	Anti-Bovine PA mouse monoclonal antibody (mAb)	1953
GMP-BOV-PA-Ab02	Anti-Bovine PA mouse monoclonal antibody (mAb)	1953
GMP-BOV-PA-Ab03	Anti-Bovine PA human monoclonal antibody (mAb)	1953
GMP-BOV-PA-Ab04	Anti-Bovine PA human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-PA-Ag01
Product Name	Recombinant Bovine PA protein
Target/Biomarker	Bovine Prealbumin (PA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine Prealbumin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
Tag	His
Products description	Recombinant Bovine PA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-PA-Ab01, GMP-BOV-PA-Ab02
Product Name	Anti-Bovine PA mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine Prealbumin (PA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine Prealbumin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies in PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
Tag	mFc
Products description	Anti-Bovine PA mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-PA-Ab03, GMP-BOV-PA-Ab04
Product Name	Anti-Bovine PA human monoclonal antibody (mAb)
Target/Biomarker	Bovine Prealbumin (PA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine Prealbumin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies in PA level test of animal Bovines/Cattle with liver disease, inflammation, or tissue death.
Tag	hFc
Products description	Anti-Bovine PA human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Bovine Prothrombin Activation Fragment 1+2 (cPAF1+2) stands as a pivotal biochemical entity within the intricate tapestry of bovine hemostasis. Structurally, it emerges as a fragment resulting from the activation of prothrombin (Factor II) into thrombin (Factor IIa) during the coagulation cascade—a process choreographed by a cascade of coagulation factors and platelet interactions. This activation event serves as the foundation of blood clot formation, a process that underpins the hemostatic equilibrium in cattle. Prothrombin, an unassuming precursor protein, circulates in the bovine bloodstream until it encounters vascular injury. When such an injury occurs, a meticulously orchestrated sequence of enzymatic reactions unfolds, culminating in the cleavage of prothrombin into two fragments: thrombin and cPAF1+2. Thrombin, the multifaceted enzyme generated through this process, assumes the central role in creating a stable blood clot. It catalyzes the conversion of soluble fibrinogen into insoluble fibrin strands, which provide the structural scaffold of a clot. In contrast, cPAF1+2 does not actively participate in clot formation but plays a pivotal role as a marker of ongoing thrombin generation within the bovine hemostatic system. Its presence in circulation serves as a dynamic reflection of the equilibrium between prothrombin activation and thrombin regulation, offering insights into the coagulation status of cattle.

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