Bovine HABP antibody and antigen (recombinant protein)

Diagnostic anti-Bovine HABP antibodies pairs and antigen for animal health (animal Bovines/Cattle rheumatoid arthritis (RA) andosteoarthritis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Ruminants disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-BOV-HABP-Ag01Bovine HABP$3090.00
GMP-BOV-HABP-Ab01Anti-Bovine HABP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-HABP-Ab02Anti-Bovine HABP mouse monoclonal antibody (mAb)$3090.00
GMP-BOV-HABP-Ab03Anti-Bovine HABP human monoclonal antibody (mAb)$3090.00
GMP-BOV-HABP-Ab04Anti-Bovine HABP human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-BOV-HABP-Ag01
Product NameBovine HABP
Target/BiomarkerBovine HABP
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Bovine HABP antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HABP level test of animal Bovines/Cattle with rheumatoid arthritis (RA) andosteoarthritis.
TagHis
Reconized/Reactive SpecicsBovine HABP
Product descriptionRecombinant Bovine HABP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-HABP-Ab01,GMP-BOV-HABP-Ab02
Target/BiomarkerBovine HABP
Product NameAnti-Bovine HABP mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Bovine HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine HABP antibodies in Bovine HABP level test of animal Bovines/Cattle with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Bovine HABP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine HABP antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-BOV-HABP-Ab03,GMP-BOV-HABP-Ab04
Target/BiomarkerBovine HABP
Product NameAnti-Bovine HABP human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Bovine HABP antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Bovine HABP antibodies in Bovine HABP level test of animal Bovines/Cattle with rheumatoid arthritis (RA) andosteoarthritis.
Product descriptionAnti-Bovine HABP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Bovine Hyaluronic Acid-Binding Protein (bHABP) stands as a pivotal biomarker in the intricate world of bovine physiology. Encoded by the bHABP gene, this glycoprotein is a member of the hyaluronic acid (HA)-binding protein family, boasting a crucial role in maintaining HA, a high molecular weight polysaccharide found abundantly in connective tissues, skin, and synovial fluid. HA's primary function is to uphold tissue hydration, lubrication, and shock absorption, and bHABP is its diligent guardian in the cattle's body.

    HA, in its unadulterated form, is a critical component of various bovine tissues, contributing significantly to the structural integrity and resilience of connective tissues. However, HA is susceptible to enzymatic degradation and environmental factors, necessitating constant surveillance and protection. This is where bHABP emerges as a key player. It binds specifically to HA molecules, forming robust associations that shield HA from degradation, thus preserving tissue hydration and lubrication.

    The importance of bHABP becomes most apparent in the context of joint health. In synovial joints, HA acts as a natural lubricant, facilitating frictionless movement. When joints lack adequate HA levels and efficient HA-binding proteins like bHABP, they become vulnerable to wear and tear, leading to conditions like osteoarthritis—a painful and debilitating ailment in cattle.

    Furthermore, bHABP's influence extends beyond joint health. It contributes to tissue hydration, ensuring that connective tissues remain pliable and resilient. This function is particularly critical for the structural integrity of the skin and mucous membranes. Additionally, bHABP has the capacity to interact with other proteins and participate in various signaling pathways, influencing processes such as tissue repair and inflammation.



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