Bovine CBS antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-CBS-Ag01	Recombinant Bovine CBS protein	3090
GMP-BOV-CBS-Ab01	Anti-Bovine CBS mouse monoclonal antibody (mAb)	1953
GMP-BOV-CBS-Ab02	Anti-Bovine CBS mouse monoclonal antibody (mAb)	1953
GMP-BOV-CBS-Ab03	Anti-Bovine CBS human monoclonal antibody (mAb)	1953
GMP-BOV-CBS-Ab04	Anti-Bovine CBS human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-CBS-Ag01
Product Name	Recombinant Bovine CBS protein
Target/Biomarker	Bovine cystathionine-β-synthase ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine cystathionine-β-synthase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	His
Products description	Recombinant Bovine CBS protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-CBS-Ab01, GMP-BOV-CBS-Ab02
Product Name	Anti-Bovine CBS mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	mFc
Products description	Anti-Bovine CBS mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-CBS-Ab03, GMP-BOV-CBS-Ab04
Product Name	Anti-Bovine CBS human monoclonal antibody (mAb)
Target/Biomarker	Bovine cystathionine-β-synthase ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine cystathionine-β-synthase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with ectopia lentis, learning difficulties and skeletal abnormalities.
Tag	hFc
Products description	Anti-Bovine CBS human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Bovine C-reactive Protein (bCRP) stands as a cornerstone biomarker in the realm of bovine health, intricately woven into the fabric of a cow's immune response to inflammatory challenges. Structurally, it is a pentameric protein, composed of five identical subunits, each boasting a molecular mass of approximately 25 kDa. Its hepatic synthesis is instigated by pro-inflammatory cytokines, most notably interleukin-6 (IL-6). The hallmark of bCRP lies in its rapid response to inflammation. When a cow confronts infectious agents, injuries, or other inflammatory triggers, the liver promptly initiates the production of bCRP. This leads to a noticeable increase in its concentration within the bloodstream, making bCRP an invaluable sentinel biomarker, capable of detecting even subtle deviations from normal health in a bovine. Functionally, bCRP serves as an acute-phase reactant, playing a pivotal role in the bovine innate immune system. It enhances opsonization and phagocytosis, bolstering the body's defenses against invading pathogens and damaged tissues. bCRP's contribution extends to the initiation of the complement cascade, further aiding in the removal of threats.

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