Bovine B2M antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-B2M-Ag01	Recombinant Bovine B2M protein	3090
GMP-BOV-B2M-Ab01	Anti-Bovine B2M mouse monoclonal antibody (mAb)	1953
GMP-BOV-B2M-Ab02	Anti-Bovine B2M mouse monoclonal antibody (mAb)	1953
GMP-BOV-B2M-Ab03	Anti-Bovine B2M human monoclonal antibody (mAb)	1953
GMP-BOV-B2M-Ab04	Anti-Bovine B2M human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-B2M-Ag01
Product Name	Recombinant Bovine B2M protein
Target/Biomarker	Avian Hepatitis E Virus ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Avian Hepatitis E Virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with renal disease.
Tag	His
Products description	Recombinant Bovine B2M protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-B2M-Ab01, GMP-BOV-B2M-Ab02
Product Name	Anti-Bovine B2M mouse monoclonal antibody (mAb)
Target/Biomarker	Avian Hepatitis E Virus ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Avian Hepatitis E Virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with renal disease.
Tag	mFc
Products description	Anti-Bovine B2M mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-B2M-Ab03, GMP-BOV-B2M-Ab04
Product Name	Anti-Bovine B2M human monoclonal antibody (mAb)
Target/Biomarker	Avian Hepatitis E Virus ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Avian Hepatitis E Virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with renal disease.
Tag	hFc
Products description	Anti-Bovine B2M human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Bovine B2M, or Beta-2 Microglobulin, stands as an unassuming yet essential player in the intricate tapestry of bovine health. This small globular protein takes center stage as a critical component of the major histocompatibility complex (MHC) class I molecules in cattle. The MHC class I molecules, in partnership with Bovine B2M, constitute the guardians of immune surveillance in cows. These molecules are akin to molecular flags displayed on the surface of virtually every nucleated cell in a bovine's body. Their pivotal role is to present fragments of intracellular pathogens or aberrant cellular proteins to cytotoxic T cells, the elite defenders of the immune system. This presentation is akin to a molecular "Wanted" poster, allowing the immune system to identify and eliminate infected or aberrant cells with precision. Bovine B2M, the guardian of MHC class I molecules, plays a vital role in ensuring their proper function. Without B2M, these molecules would not be efficiently transported to the cell surface or would be prone to premature degradation, compromising immune surveillance. Bovine B2M stands as the molecular custodian, upholding the vigilance of the immune system and ensuring that threats are swiftly detected and neutralized.

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