Bovine ANP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-BOV-ANP-Ag01	Recombinant Bovine ANP protein	3090
GMP-BOV-ANP-Ab01	Anti-Bovine ANP mouse monoclonal antibody (mAb)	1953
GMP-BOV-ANP-Ab02	Anti-Bovine ANP mouse monoclonal antibody (mAb)	1953
GMP-BOV-ANP-Ab03	Anti-Bovine ANP human monoclonal antibody (mAb)	1953
GMP-BOV-ANP-Ab04	Anti-Bovine ANP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-BOV-ANP-Ag01
Product Name	Recombinant Bovine ANP protein
Target/Biomarker	Bovine atrial natriuretic peptide ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Bovine atrial natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
Tag	His
Products description	Recombinant Bovine ANP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-ANP-Ab01, GMP-BOV-ANP-Ab02
Product Name	Anti-Bovine ANP mouse monoclonal antibody (mAb)
Target/Biomarker	Bovine atrial natriuretic peptide ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Bovine atrial natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
Tag	mFc
Products description	Anti-Bovine ANP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-BOV-ANP-Ab03, GMP-BOV-ANP-Ab04
Product Name	Anti-Bovine ANP human monoclonal antibody (mAb)
Target/Biomarker	Bovine atrial natriuretic peptide ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Bovine atrial natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Bovines/Cattle with hypertension, cardiac hypertrophy and heart failure.
Tag	hFc
Products description	Anti-Bovine ANP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

o delve deeper into the nature of hANP, it's essential to understand its molecular structure and physiological functions in detail. Human Atrial Natriuretic Peptide is composed of 28 amino acids, with a molecular weight of approximately 3.5 kDa. Its synthesis predominantly occurs in the cardiac atria in response to stretch receptors being activated due to increased atrial pressure or volume, a phenomenon observed during conditions such as congestive heart failure or volume expansion.Once synthesized and released into circulation, hANP exerts its effects primarily through binding to specific receptors, known as natriuretic peptide receptors (NPRs), located in various tissues, including the kidneys, blood vessels, and adrenal glands. Binding of hANP to NPRs initiates a signaling cascade that leads to vasodilation, increased glomerular filtration rate, and enhanced sodium excretion in the kidneys. These combined actions result in reduced blood volume, lower blood pressure, and maintenance of fluid and electrolyte balance. While the structural and functional aspects of hANP are well-conserved between humans and cattle, there may be subtle species-specific differences in the regulation of hANP expression and receptor distribution. Understanding these nuances is critical for tailoring diagnostic and therapeutic approaches in bovines effectively.

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