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Anti-I17RE/ IL17RE monoclonal antibody
Anti-I17RE/ IL17RE antibody for FACS & in-vivo assay
Go to IL17RE/IL17RE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-TA182-Ab-1/ GM-Tg-hg-TA182-Ab-2 | Anti-Human IL17RE monoclonal antibody | Human |
| GM-Tg-rg-TA182-Ab-1/ GM-Tg-rg-TA182-Ab-2 | Anti-Rat IL17RE monoclonal antibody | Rat |
| GM-Tg-mg-TA182-Ab-1/ GM-Tg-mg-TA182-Ab-2 | Anti-Mouse IL17RE monoclonal antibody | Mouse |
| GM-Tg-cynog-TA182-Ab-1/ GM-Tg-cynog-TA182-Ab-2 | Anti-Cynomolgus/ Rhesus macaque IL17RE monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-TA182-Ab-1/ GM-Tg-felg-TA182-Ab-2 | Anti-Feline IL17RE monoclonal antibody | Feline |
| GM-Tg-cang-TA182-Ab-1/ GM-Tg-cang-TA182-Ab-2 | Anti-Canine IL17RE monoclonal antibody | Canine |
| GM-Tg-bovg-TA182-Ab-1/ GM-Tg-bovg-TA182-Ab-2 | Anti-Bovine IL17RE monoclonal antibody | Bovine |
| GM-Tg-equg-TA182-Ab-1/ GM-Tg-equg-TA182-Ab-2 | Anti-Equine IL17RE monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-TA182-Ab-1/ GM-Tg-hg-TA182-Ab-2; GM-Tg-rg-TA182-Ab-1/ GM-Tg-rg-TA182-Ab-2; GM-Tg-mg-TA182-Ab-1/ GM-Tg-mg-TA182-Ab-2; GM-Tg-cynog-TA182-Ab-1/ GM-Tg-cynog-TA182-Ab-2; GM-Tg-felg-TA182-Ab-1/ GM-Tg-felg-TA182-Ab-2; GM-Tg-cang-TA182-Ab-1/ GM-Tg-cang-TA182-Ab-2; GM-Tg-bovg-TA182-Ab-1/ GM-Tg-bovg-TA182-Ab-2; GM-Tg-equg-TA182-Ab-1/ GM-Tg-equg-TA182-Ab-2 |
| Products Name | Anti-IL17RE monoclonal antibody |
| Format | mab |
| Target Name | IL17RE |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-IL17RE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species I17RE/ IL17RE VLP (virus-like particle) (Products Developing) |
| Cytokine | GM-Tg-g-TA182-Ag-1 | interleukin 17 receptor E (IL17RE) protein |
Target information
| Target ID | GM-TA182 |
| Target Name | IL17RE |
| Gene ID | 132014,57890,362417,698972,484661,101091853,783335,100052054 |
| Gene Symbol and Synonyms | IL-17RE,IL17RE,Il25r |
| Uniprot Accession | Q8NFR9,Q6AZ51 |
| Uniprot Entry Name | I17RE_HUMAN,I17RE_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | Therapeutics Target, Cytokine Target |
| Disease | N/A |
| Gene Ensembl | ENSG00000163701 |
| Target Classification | N/A |
The target: IL17RE, gene name: IL17RE, also named as . This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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