Anti-PCAT2/ LPCAT2/ AGPAT11 monoclonal antibody

Anti-PCAT2/ LPCAT2/ AGPAT11 antibody for FACS & in-vivo assay

Target products collectionGo to LPCAT2/LPCAT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-TA099-Ab-1/ GM-Tg-hg-TA099-Ab-2Anti-Human LPCAT2 monoclonal antibodyHuman
GM-Tg-rg-TA099-Ab-1/ GM-Tg-rg-TA099-Ab-2Anti-Rat LPCAT2 monoclonal antibodyRat
GM-Tg-mg-TA099-Ab-1/ GM-Tg-mg-TA099-Ab-2Anti-Mouse LPCAT2 monoclonal antibodyMouse
GM-Tg-cynog-TA099-Ab-1/ GM-Tg-cynog-TA099-Ab-2Anti-Cynomolgus/ Rhesus macaque LPCAT2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-TA099-Ab-1/ GM-Tg-felg-TA099-Ab-2Anti-Feline LPCAT2 monoclonal antibodyFeline
GM-Tg-cang-TA099-Ab-1/ GM-Tg-cang-TA099-Ab-2Anti-Canine LPCAT2 monoclonal antibodyCanine
GM-Tg-bovg-TA099-Ab-1/ GM-Tg-bovg-TA099-Ab-2Anti-Bovine LPCAT2 monoclonal antibodyBovine
GM-Tg-equg-TA099-Ab-1/ GM-Tg-equg-TA099-Ab-2Anti-Equine LPCAT2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-TA099-Ab-1/ GM-Tg-hg-TA099-Ab-2; GM-Tg-rg-TA099-Ab-1/ GM-Tg-rg-TA099-Ab-2;
GM-Tg-mg-TA099-Ab-1/ GM-Tg-mg-TA099-Ab-2; GM-Tg-cynog-TA099-Ab-1/ GM-Tg-cynog-TA099-Ab-2;
GM-Tg-felg-TA099-Ab-1/ GM-Tg-felg-TA099-Ab-2; GM-Tg-cang-TA099-Ab-1/ GM-Tg-cang-TA099-Ab-2;
GM-Tg-bovg-TA099-Ab-1/ GM-Tg-bovg-TA099-Ab-2; GM-Tg-equg-TA099-Ab-1/ GM-Tg-equg-TA099-Ab-2
Products NameAnti-LPCAT2 monoclonal antibody
Formatmab
Target NameLPCAT2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody, Therapeutics Target antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-LPCAT2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PCAT2/ LPCAT2/ AGPAT11 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-TA099
    Target NameLPCAT2
    Gene ID54947,270084,100359680,698605,611330,101099093,514646,100061308
    Gene Symbol and Synonyms1-AGPAT 11,A330042H22,AGPAT11,AYTL1,Aytl1a,lpafat1,LPCAT-2,LPCAT2,LPLAT9,LysoPAFAT,lysoPAFAT/LPCAT2,RGD1563994
    Uniprot AccessionQ7L5N7,P0C1Q3
    Uniprot Entry NamePCAT2_HUMAN,PCAT2_RAT
    Protein Sub-locationTransmembrane Protein
    CategoryTherapeutics Target
    DiseaseN/A
    Gene EnsemblENSG00000087253
    Target ClassificationN/A

    The target: LPCAT2, gene name: LPCAT2, also named as AGPAT11, AYTL1, LysoPAFAT. This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.